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OverviewDiabetes mellitus (DM) is a heterogeneous disorder resulting from an interaction of numerous genetic and environmental factors. It is a disease that has strong clustering in families and has genetic component. Current study was aimed to determine familial clustering, inheritance pattern and the influence of consanguineous marriages on the aggregation of type 2 diabetes mellitus in a sample population of Balouch community. Study was further extended towards the estimation of antioxidant enzyme activities and lipid peroxidation in diabetic subjects in Balouch and Punjabi community. Lipid peroxidation product of thiobarbituric acid compound (malondialdehyde MDA) was used as indicator of membrane damage while levels of antioxidant enzymes were considered as markers for vascular injury. In conclusion, Family history index was found to be a useful parameter used to measure the risk for developing type 2 DM. Consanguinity plays an important role in the aggregation of type 2 DM in families having diabetic subjects. Offsprings and siblings of type 2 DM patients have a greater risk to developing diabetes at any time during their life span. Full Product DetailsAuthor: Feroza Ahmed , Farzana NaqviPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 1.10cm , Length: 22.90cm Weight: 0.295kg ISBN: 9783846520857ISBN 10: 3846520853 Pages: 196 Publication Date: 15 October 2011 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |