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OverviewFull Product DetailsAuthor: Kenneth S. Kendler , Carol A. Prescott , Matthew McGue , Robert PlominPublisher: Guilford Publications Imprint: Guilford Publications Dimensions: Width: 15.60cm , Height: 2.80cm , Length: 23.40cm Weight: 0.606kg ISBN: 9781593856458ISBN 10: 1593856458 Pages: 412 Publication Date: 17 January 2008 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Paperback Publisher's Status: Out of Print Availability: In Print  Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock. Table of ContentsIntroduction I. Background 1. The Scientific and Social Context of the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders 2. Methodology Used in the VATSPSUD 3. Twinning and Twin Models II. Genetic Risk 4. Internalizing Disorders 5. Externalizing and Substance Use Disorders 6. Twin Model Assumptions III. Environmental Risk 7. Childhood Experiences and Risk for Psychopathology 8. Adult Experiences and Risk for Psychopathology IV. A Closer Look at Genetic and Environmental Influences 9. Sex Differences 10. Genetic and Environmental Influences on Stability and Change 11. The Genetics of What?: Comorbidity, General versus Specific Effects, and Risk Indicators 12. Three Extensions of the Twin Model V. Bringing it All Together 13. The Genetics of the Environment 14. Mechanisms for Genetic Control of Exposure to the Environment 15. Is the Relation between Environmental Risk Factors and Psychiatric Disorders Causal? 16. Genetic Control of Sensitivity to the Environment 17. Integrative Models 18. ConclusionsReviewsOver the last 20 years, it is likely that no other single study has had a greater impact on academic psychiatry than the Virginia Adult Twin Study, which has been instrumental in ushering in the current genomics era in biological psychiatry. Kendler and Prescott have done the field an immeasurable service by placing the major findings from the study under a single cover. - Matt McGue, PhD, Department of Psychology, University of Minnesota, USA This most engaging book by world leaders in psychiatric genetics is an essential read... It provides a lively, balanced, informative conceptual understanding of how genes and environment work together in causal pathways as they operate over time. - Michael Rutter, MD, FRS, Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, UK For students, the straightforward and highly informative details of the methods used to test major and ancillary questions will be particularly valuable. Scientists, for their part, will benefit from having a single, well-referenced source on this excellent study. - Marc A. Schuckit, MD, Department of Psychiatry, University of California, San Diego; Alcohol Research Center, VA San Diego Healthcare System, USA Clear, thoughtful, and timely... This book is a gift to all those willing to embrace the underlying complexity of psychiatric disorders and substance abuse. - Twin Research and Human Genetics Over the last 20 years, it is likely that no other single study has had a greater impact on academic psychiatry than the Virginia Adult Twin Study, which has been instrumental in ushering in the current genomics era in biological psychiatry. Kendler and Prescott have done the field an immeasurable service by placing the major findings from the study under a single cover. - Matt McGue, PhD, Department of Psychology, University of Minnesota, USA This most engaging book by world leaders in psychiatric genetics is an essential read... It provides a lively, balanced, informative conceptual understanding of how genes and environment work together in causal pathways as they operate over time. - Michael Rutter, MD, FRS, Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, UK For students, the straightforward and highly informative details of the methods used to test major and ancillary questions will be particularly valuable. Scientists, for their part, will benefit from having a single, well-referenced source on this excellent study. - Marc A. Schuckit, MD, Department of Psychiatry, University of California, San Diego; Alcohol Research Center, VA San Diego Healthcare System, USA Clear, thoughtful, and timely... This book is a gift to all those willing to embrace the underlying complexity of psychiatric disorders and substance abuse. - Twin Research and Human Genetics ""Over the last 20 years, it is likely that no other single study has had a greater impact on academic psychiatry than the Virginia Adult Twin Study, which has been instrumental in ushering in the current genomics era in biological psychiatry. Kendler and Prescott have done the field an immeasurable service by placing the major findings from the study under a single cover."" - Matt McGue, PhD, Department of Psychology, University of Minnesota, USA ""This most engaging book by world leaders in psychiatric genetics is an essential read... It provides a lively, balanced, informative conceptual understanding of how genes and environment work together in causal pathways as they operate over time."" - ""Michael Rutter, MD, FRS, Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, UK ""For students, the straightforward and highly informative details of the methods used to test major and ancillary questions will be particularly valuable. Scientists, for their part, will benefit from having a single, well-referenced source on this excellent study."" -"" ""Marc A. Schuckit, MD, Department of Psychiatry, University of California, San Diego; Alcohol Research Center, VA San Diego Healthcare System, USA ""Clear, thoughtful, and timely... This book is a gift to all those willing to embrace the underlying complexity of psychiatric disorders and substance abuse."" - Twin Research and Human Genetics Author InformationKenneth S. Kendler, MD, is the Banks Distinguished Professor of Psychiatry and Professor of Human Genetics at the Medical College of Virginia, Virginia Commonwealth University. Since 1983, he has been engaged in studies of the genetics of psychiatric and substance use disorders, and he has been the director of the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders since its inception. Dr. Kendler's work has utilized the methods of both large-scale population-based twin studies and molecular genetics. He has published over 430 peer-reviewed articles, has received a number of national and international awards, is a member of the Institute of Medicine of the National Academy of Sciences, serves on several editorial boards, and is Editor of Psychological Medicine. Since 1996, Dr. Kendler has served as Director of the Virginia Institute for Psychiatric and Behavioral Genetics. Carol A. Prescott, PhD, is Professor of Psychology at the University of Southern California. From 1992 to 2005, she was on the faculty of the Virginia Institute for Psychiatric and Behavioral Genetics of Virginia Commonwealth University, where she served as Co-Director of the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders. Dr. Prescott has published extensively on genetic influences on alcoholism and other forms of psychopathology. She serves as Associate Editor for Behavior Genetics and Alcoholism: Clinical and Experimental Research. Her honors include election to membership in the Society for Multivariate Experimental Psychology and the Theodore Reich Prize from the International Society on Psychiatric Genetics. Tab Content 6Author Website:Countries AvailableAll regions |
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