Overview

Signalling by morphogens such as the Hedgehog family, Notch, Wingless/Wnt and various growth factors is essential during embryogenesis. The establishment of concentration gradients of these morphogens plays a key role during developmental patterning in all multicellular organisms, assuring that distinct cell/tissue types and organs appear at the right place in the right time during embryogenesis. Regulation of morphogen synthesis, trafficking and diffusion are all known to play a part in setting up these gradients, and a complex web of signaling mechanisms ensures that specific responses occur at the correct threshold concentration in the recipient cells whose fate depends on these morphogens.

Full Product Details

Author:   James Briscoe ,  Jean-Paul Vincent ,  Peter Lawrence
Publisher:   Cold Spring Harbor Laboratory Press,U.S.
Imprint:   Cold Spring Harbor Laboratory Press,U.S.
Dimensions:   Width: 17.80cm , Height: 5.00cm , Length: 25.40cm
Weight:   0.862kg
ISBN:  

9780879698812

ISBN 10:   0879698810
Pages:   900
Publication Date:   22 March 2010
Audience:   College/higher education ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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