Overview

The succesful introduction of a gene sequence in somatic cells followed by long-term expression at therapeutic levels can fundamentally correct a variety of inherited and acquired diseases. Therefore gene therapy holds great promise in the field of clinical and molecular medicine. This volume summarizes recent advances in the field. It emphasizes the influence of chromatin structure on gene expression, describes the the principal mechanisms of gene expression, epigenic elements, viral vectors, non-viral vectors as gene delivery systems, animal models of human diseases, inducible regulatory systems, gene therapy of cancer, AIDS, monogenic disorders, and ongoing clinical trials.

Full Product Details

Author:   K. Xanthopoulos (National Institutes of Health, Bethesda, Maryland, USA)
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   illustrated edition
Volume:   Vol 105
Weight:   0.550kg
ISBN:  

9783540641124

ISBN 10:   3540641122
Pages:   231
Publication Date:   20 May 1998
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Temporarily unavailable  
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