Overview

Gene Therapy describes the delivery systems now available to target a given tissue with specific gene or oligonucleotide sequences, and explores the utility of animal modules as test systems. In the context of selected disease states, it summarises in vitro and in vivo studies and clinical trials performed to date.

Full Product Details

Author:   David Cooper (University of Wales, UK) ,  Prof Nick Lemoine
Publisher:   Taylor & Francis Ltd
Imprint:   Bios Scientific Publishers Ltd
Dimensions:   Width: 15.60cm , Height: 2.00cm , Length: 23.40cm
Weight:   0.748kg
ISBN:  

9781859962053

ISBN 10:   185996205
Pages:   360
Publication Date:   15 June 1996
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Scope and limitations of gene therapy, K. Sikora. Tissue-directed gene delivery systems, C.R. Middaugh et al. Retroviral vectors, W.H. Gunzburg and B. Salmons. Adenovirus vectors, C.J.A. Ring. Adeno-associated virus vectors for human gene therapy, J.S. Bartlett and R.J. Samulski. Liposome delivery systems, R.K. Scheule and S.H. Cheng. Development of mammalian artificial chromosome vectors: prospects for somatic gene transfer, Z. Larin. Infectious herpes vectors for gene therapy, J.-M.H. Vos et al. Role of animal models in gene therapy, J.R. Dorin and D.J. Porteous. Gene targeting as an approach to gene therapy, A. Porter. Cystic fibrosis, N.J. Caplen and E.W.F.W. Alton. Gene therapy for haemophilia B, K. Kurachi and J.-M. Wang. Gene therapy for adenosine deaminase deficiency, H.B. Gaspar and C. Kinnon. Cardiovascular disease, B.A. French. Cancer gene therapy I: genetic intervention strategies, L.-A. Martin and N.R. Lemoine. Cancer gene therapy II: immunomodulation strategies, J. Galea-Lauri and J. Gaken. The muscular dystrophies, C.A. Sewry and T.A. Partridge. Recent developments in gene therapy for neurological disorders, P.R. Lowenstein.

Reviews

'Extremely well written and well documented and gives a balanced view of a complex area of scientific endeavor.' - Genetical Research 'Enjoyable and easy to read good use made of illustrations and tables and excellent and comprehensive review of the major topics associated with gene therapy, and it should become a standard reference for anyone in the field.' - Molecular Medicine Today 'I recommend it to anyone wishing to find out more about gene therapy, whether they are a qualified clinician, basic scientist or student in training.' - Biologist

'Extremely well written and well documented and gives a balanced view of a complex area of scientific endeavor.' - Genetical Research 'Enjoyable and easy to read good use made of illustrations and tables and excellent and comprehensive review of the major topics associated with gene therapy, and it should become a standard reference for anyone in the field.' - Molecular Medicine Today 'I recommend it to anyone wishing to find out more about gene therapy, whether they are a qualified clinician, basic scientist or student in training.' - Biologist

Author Information

Cooper, David; Lemoine, Prof Nick

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