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OverviewThe sequencing projects opened unprecedented possibilities of investigating complex aspects of living organisms. Among the high-throughput technologies based on genomic sequences, microarrays are widely used for measuring the relative quantity of messenger RNAs. The analysis of microarrays aims at selecting genes whose expression is different in different conditions followed by grouping them in functional categories, enabling a biological interpretation of the results. Methods to analyze microarray data are explored in this book. Not all the genes present in human cells are active; the housekeeping genes are expressed ubiquitously. Other genes (the tissue-selective genes) provide specific functions and they are expressed in certain cell types or tissues. Defining the tissue-selective genes is important as these genes cause disease with phenotype in the tissues where they are expressed. In this study, gene expression data is used for creating a catalog of genes in healthy human tissues. Moreover, the analysis of promoter sequences is used to predict gene networks and highlighting modules of transcription factors playing a role in the regulation of transcription. Full Product DetailsAuthor: Dario GrecoPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 0.40cm , Length: 22.90cm Weight: 0.118kg ISBN: 9783838319223ISBN 10: 3838319222 Pages: 72 Publication Date: 06 June 2010 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In Print This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |