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OverviewGap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants. Full Product DetailsAuthor: Ekrem Dere (Physiological Psychology, University of Düsseldorf, Germany)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Dimensions: Width: 21.60cm , Height: 2.30cm , Length: 27.60cm Weight: 1.100kg ISBN: 9780124159013ISBN 10: 012415901 Pages: 304 Publication Date: 03 October 2012 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsSection I: Physiology of gap junctions in the brain Section II: Gap junctions between astrocytes, neurons, and glia-neuron interactions Section III: The role of gap junctions in brain development, neurogenesis and synaptic plasticity Section IV: Gap junctions and neuronal synchronization Section V: Gap junctions and neurological and neuropsychiatric diseases Section VI: Gap junctions and behaviorReviews"""Dere.introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction- related diseases due to mutations in connexin genes. International researchers working in this emerging field discuss specific connexin genes and their mechanisms of action and function in the developing neocortx, behavior, and neurological and neuropsychiatric diseases.""--Reference and Research Book News, February 2013" Dere.introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction- related diseases due to mutations in connexin genes. International researchers working in this emerging field discuss specific connexin genes and their mechanisms of action and function in the developing neocortx, behavior, and neurological and neuropsychiatric diseases. --Reference and Research Book News, February 2013 Dere.introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction- related diseases due to mutations in connexin genes. International researchers working in this emerging field discuss specific connexin genes and their mechanisms of action and function in the developing neocortx, behavior, and neurological and neuropsychiatric diseases. --Reference and Research Book News, February 2013 Author InformationEkrem Dere is full professor for the Pathophysiology of Cerebral Aging at the Pierre et Marie Curie University in Paris, France. His former team at the University in Düsseldorf, Germany, has provided the first behavioral evidence demonstrating that gap junctions in the brain play an important role in various behavioral processes. Tab Content 6Author Website:Countries AvailableAll regions |
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