From Bench to Market: The Evolution of Chemical Synthesis

Author:   Walter Cabri (R&D Director, Antibioticos, Rodano) ,  Romano Di Fabio (Head of CNS Medicinal Chemistry, Glaxo-Wellcome)
Publisher:   Oxford University Press
ISBN:  

9780198503842


Pages:   282
Publication Date:   19 October 2000
Format:   Hardback
Availability:   Out of stock   Availability explained


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From Bench to Market: The Evolution of Chemical Synthesis


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Overview

' I highly recommend this book to process chemists not only in the pharmaceutical industry but in the fine chemical, agrochemical, and colour chemical industries too... highly recommened - I will certainly use it as a teaching aid ' Chemistry in IndustryWho wins the race to turn molecules into medicines? How much does it cost? What factors influence the choice of synthetic routes and reaction mechanisms? How can pharmaceutical companies protect their discoveries? In From Bench to Market, Walter Cabri and Romano Di Fabio chart the process of industrial chemical synthesis, from the first discovery of a molecule to its entry in the marketplace as a drug. Using real case histories of drug development from several therapeutic areas, they discuss all aspects related to the process research for bulk production, including comparison between different synthetic routes, key methodologies and reaction mechanisms, costs, patent competition, and crystalline forms.

Full Product Details

Author:   Walter Cabri (R&D Director, Antibioticos, Rodano) ,  Romano Di Fabio (Head of CNS Medicinal Chemistry, Glaxo-Wellcome)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Dimensions:   Width: 19.40cm , Height: 2.10cm , Length: 25.30cm
Weight:   0.698kg
ISBN:  

9780198503842


ISBN 10:   0198503849
Pages:   282
Publication Date:   19 October 2000
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock   Availability explained

Table of Contents

Preface 1: Process research and development: The modern approach 2: Non-classical ß-lactam antibiotics 3: Imipenem 4: Sanfetrinems 5: Ritipenems 6: Losartan 7: Nabumetone 8: Acyclovir 9: Idarubicin 10: Paclitaxel 11: The drug discovery process: Towards a new paradigm

Reviews

""" I highly recommend this book to process chemists not only in the pharmaceutical industry but in the fine chemical, agrochemical, and colour chemical industries too ... highly recommened - I will certainly use it as a teaching aid "" Chemistry in Industry"


I highly recommend this book to process chemists not only in the pharmaceutical industry but in the fine chemical, agrochemical, and colour chemical industries too ... highly recommened - I will certainly use it as a teaching aid Chemistry in Industry


Author Information

Walter Cabri, R+D Director, Research and Development, Antibioticos, Rodano, Italy wcabri@antibioticos.it Romano Di Fabio, Head of CNS Medicinal Chemistry, Medicines and Research Centre, Glaxo- Wellcome, Verona, Italy rdf26781@glaxowellcome.co.uk

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