Overview

Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research since its first publication in 1985. This latest edition has been comprehensively rewritten and updated (over 80% of the text is new), whilst maintaining the clarity of its predecessor. There is expanded coverage of isoprostanes and related compounds, mechanisms of oxidative damage to DNA and proteins (and the repair of such damage), the free radical theory of ageing and the roles played by reactive species in signal transduction, cell death, human reproduction, and other important biological events. Greater emphasis has also been placed on the methods available to measure reactive species and oxidative damage (and their potential pitfalls), as well as the importance of antioxidants in the human diet. This book is recommended as a comprehensive introduction to the field for students, clinicians and researchers, and an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Full Product Details

Author:   Halliwell ,  Gutteridge
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Edition:   4th edition
Dimensions:   Width: 18.90cm , Height: 4.80cm , Length: 24.60cm
Weight:   2.093kg
ISBN:  

9780198568681

ISBN 10:   0198568681
Pages:   888
Publication Date:   08 March 2007
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   To order  
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.

Table of Contents

1. Oxygen is a toxic gas - an introductionto oxygen toxicity and reactive species; 2. The chemistry of free radicals and related 'reactive species'; 3. Antioxidant defences; Endogenous and Diet Derived; 4. Cellular responses to oxidative stress: adaptation, damage, repair, senescence and death; 5. Measurement of reactive species; 6. Reactive species can pose special problems needing special solutions. Some examples.; 7. Reactive species can be useful; some more examples; 8. Reactive species can be poisonous: their role in toxicology; 9. Reactive species and disease: fact, fiction or filibuster?; 10. Ageing, nutrition, disease, and therapy: A role for antioxidants?

Reviews

"`Review from previous edition ""...This new tome has exceeded all my expectations."" ""...Free Radicals in Biology and Medicine...has always been compulsive reading for all in this area of research whether undergraduate, postgraduate undertaking a PhD programme, clinician, or scientist and a veyr popular text for teachers and students alike...The new volume not only continues this tradition, it is also a superb triumph of a textbook from two eminent leaders in the field and a must for anyone wanting to come to grips with the diverse area of free radical research and its relevance to biology and human disease, or for experts to bring themselves up to date with the areas that they do not normally focus on.""' Prof. Catherine Rice-Evans, Guy's, King's and St. Thomas's School of Medicine and Dentistry ."

`Review from previous edition ...This new tome has exceeded all my expectations. ...Free Radicals in Biology and Medicine...has always been compulsive reading for all in this area of research whether undergraduate, postgraduate undertaking a PhD programme, clinician, or scientist and a veyr popular text for teachers and students alike...The new volume not only continues this tradition, it is also a superb triumph of a textbook from two eminent leaders in the field and a must for anyone wanting to come to grips with the diverse area of free radical research and its relevance to biology and human disease, or for experts to bring themselves up to date with the areas that they do not normally focus on. ' Prof. Catherine Rice-Evans, Guy's, King's and St. Thomas's School of Medicine and Dentistry .

Author Information

Professor Barry Halliwell, Department of Pharmacology, King's College, London. John M. C. Gutteridge, Department of Anaesthesia and Intensive Care, Royal Brompton Hospital, London

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