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OverviewProvides insight into the involvement of free radicals in the pathogenesis of chemical-induced toxic tissue injury. The text addresses the fundamentals of free radical chemistry and the theoretical basis for electron transfer reaction leading to free radical generation. It describes the various subcellular sources of free radicals, the biological reactivity with lipid, protein and nucleic acids, and the physiochemical determinants of free radical-induced cell injury and the various antioxidant defence systems. The book focuses on target organ toxicity, and the concluding section offers an overview of the evidence implicating free radicals in the aetiology of various chemical toxicities, challenging the possibility of misguided use of biomarkers for oxidative damage. Full Product DetailsAuthor: Kendall B WallacePublisher: Taylor & Francis Inc Imprint: Taylor & Francis Inc Edition: 2nd Revised edition Dimensions: Width: 15.20cm , Height: 3.00cm , Length: 22.90cm Weight: 0.835kg ISBN: 9781560326328ISBN 10: 1560326328 Pages: 352 Publication Date: 19 June 1997 Audience: Professional and scholarly , Professional and scholarly , Professional & Vocational , Professional & Vocational Format: Hardback Publisher's Status: Out of Stock Indefinitely Availability: Out of stock  Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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