Overview

This is a concise summary of knowledge about skeletal muscle fibres. The fibre types are characterized from different points of view. The difficulties and possibilities of classifying muscle fibres in distinct non-overlapping types are shown. A main emphasis is put on metabolic fibre typing by cytophotometry as well as the adaptability of a given fibre type to altered physiological and pathological conditions. Extensive analyses of several rat hindlimb muscles revealed regional differences of fibre properties within the muscles and showed the influence of ageing, myopathy, hypoxia, diabetes and Ginkgo biloba-treatment on the different fibre types.

Full Product Details

Author:   Karla Punkt
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 2002
Volume:   162
Dimensions:   Width: 15.50cm , Height: 0.70cm , Length: 23.50cm
Weight:   0.260kg
ISBN:  

9783540426035

ISBN 10:   3540426035
Pages:   112
Publication Date:   14 December 2001
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Awaiting stock  
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Table of Contents

1 Introduction.- 1.1 General Remarks.- 1.2 Structure and Contraction Mechanism of Muscle Fibres.- 1.3 Intrafusal Fibres of Muscle Spindles.- 1.4 Satellite Cells.- 2 When Does Differentiation of Muscle Fibres Begin and Which Properties Characterize a Fibre Type? How Can the Muscle Fibre “Know” Whether to Be Fast or Slow, and Since When?.- 3 The Difficulties and Possibilities of Classifying Muscle Fibres in Distinct Nonoverlapping Types.- 4 Cytophotometry As a Tool in Fibre Typing.- 4.1 The Basic Principle.- 4.2 The Enzymes Which Are Useful for Cytophotometrical Fibre Typing.- 4.3 The Physiological-Metabolic Muscle Fibre Typing By Cytophotometry.- 4.4 The Reliability of Cytophotometrical Data.- 5 Changes of Muscle Fibre Properties Under Physiological and Pathological Conditions.- 5.1 Regional Differences.- 5.2 Development and Ageing.- 5.3 Hereditary Myopathy.- 5.4 Experimental Acute Hypoxia.- 5.5 Streptozotocin-Induced Diabetes.- 6 Fibre Type Transformation.- 6.1 Conclusions.- 7 FOG Fibres — The Most Adaptable Muscle Fibres.- 8 Are There Adaption Processes in -?—Motoneurons as in Muscle Fibres?.- 9 The Influence of the Muscle Type on the Properties of a Fibre Type.- 10 Correspondences Between Physiological—Metabolic Fibre Typing, ATPase-Fibre Typing and Differentiation of Myosin Isoforms.- 11 Expression of Nitric Oxide Synthase Isoforms and Protein Kinase-C? in the Different Fibre Types and Alterations by Diabetes and EGb 761 Pretreatment.- 11.1 Illustration of the Topic.- 11.2 Experimental Basis.- 11.3 The Correlation of NOSI, NOSIII and PKC? to the Fibre Types.- 11.4 The Effect of STZ-Induced Diabetes and EGb 761 on the Expression of NOSI and NOSIII in the Rat Vastus Lateralis Muscle.- 11.5 NOSII Expression in Skeletal Muscle Fibres.- 11.6 Conclusions.- 12Specific Muscle Fibre Types of Extraocular Muscles.- 12.1 The Complexity of Extraocular Muscles.- 12.2 Fibre Types of Extraocular Muscles.- 12.3 Summary.- 13 Summary.- 14 Conclusions.- References.

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