Overview

Leading bench-top experimentalists from around the world present, in a proven format, their state-of-the-art methods for probing the extracellular matrix (ECM), its mechanisms of assembly and how it influences cell behavior. These carefully detailed biochemical, biophysical, genetic, molecular biological, and cell biological techniques have been optimized for the study of ECM structure and assembly, the mechanisms of cell ECM interactions, and the molecular genetics of ECM proteins and defects in human disease, and bring to a wider audience a range of highly sophisticated methods that have hitherto been difficult even for a few specialized laboratories. Cutting-edge and highly practical, Extracellular Matrix Protocols offers today's ECM researchers a gold-standard collection of powerful, readily reproducible methods to investigate the extracellular matrix and the altered cell ECM interactions that play so important a role in human health and disease.

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9780896036246

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This would be most useful to a lab researcher who had not previously been studying the role of the ECM in biological systems, and who wished to do so. Having all the practical protocols for preparing, assaying, and studying these important molecules in a small volume could be very useful for such a researcher. -Doody's Health Science Book Review Journal

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