Exploring Genetic Mechanisms

Author:   Maxine Singer ,  Paul Berg
Publisher:   University Science Books,U.S.
ISBN:  

9780935702705


Pages:   616
Publication Date:   07 May 1997
Format:   Hardback
Availability:   Out of stock   Availability explained


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Exploring Genetic Mechanisms


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Overview

An outstanding group of scientists have collaborated in the collection of case studies that comprise this major text-reference book. It examines in detail how genes operate in diverse living systems, including viruses, cells and more complex organisms; investigates how genotypes can be altered; and looks at the mapping and sequencing of human and other genomes. Students and professionals in biochemistry, molecular biology and genetics will enjoy this book.

Full Product Details

Author:   Maxine Singer ,  Paul Berg
Publisher:   University Science Books,U.S.
Imprint:   University Science Books,U.S.
Dimensions:   Width: 22.50cm , Height: 4.00cm , Length: 28.50cm
Weight:   1.980kg
ISBN:  

9780935702705


ISBN 10:   0935702709
Pages:   616
Publication Date:   07 May 1997
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock   Availability explained

Table of Contents

Mammalian DNAViruses: Papovaviruses as Models of Cellular Genetic Functions and Oncogenesis.- Eukaryotic RNA Viruses: A Variant Genetic System.- Retroviruses, Infectious Genetic Elements.- Oncogenes.- Mapping Markers and Genes in the Human Genome.- Molecular Genetics of the Hemoglobin Gene.- Arrangement and Rearrangement of Genes Controlling the Immune System.- Biosynthesis of Intercellular Messenger Peptides.- Regulation of Early Drosophila Development.- Manipulating Protein Structure.- Genetic Modification of Animals.- Genetic Modification of Plants.

Reviews

In their earlier volumes, Singer & Berg have laid out the fundamentals of modern molecular biology. Here, with a group of the finest co-authors, they focus on the individual stories that make biology such a rich and varied science. The genes come alive as individual pieces of the biological tapestry. Viral genes, hemoglobin genes, genes for antibodies, genes of plants oncogenes and many more are probed along with the methodologies used to investigate them. A great volume from which to learn or teach about how actual life emerges from the four bases that make up DNA. --David Baltimore, President-Elect California Institute of Technology The textbook Exploring Genetic Mechanisms is an excellent account of the hallmarks of modern genetic analysis...[It] takes its readers through a detailed account of many fundamental principles of molecular genetics. It provides specific examples of well-characterized genetic mechanisms that operate within a gene family as well as examples of more complex genetic relations that operate within an entire organism. This book represents the next generation of modern genetics textbooks and will be invaluable for genetics researchers and students. --The New England Journal of Medicine


Like its two two predecessors (Dealing with Genes, and Genes and Genomes), Exploring Genetic Mechanisms shows the result of thoughtful organization of content and careful editing. It succeeds in its purpose to familiarize the reader with the many different ways molecular genetics is being used to unravel and to understand the complex mechanisms involved in the development of a living organism from a collection of genes found in DNA...all chapters carry the superb writing style of Singer and Berg, who provide the unifying overviews and insights. The overall quality of Exploring Genetic Mechanisms (and of Genes and Genomes) is such that both can serve as models for any scientific work. Upper-division undergraduates through professionals. --Choice The currency of the coverage and the clarity of the diagrams are wonderful. It is a rare delight to have such complete coverage of the major topic areas written in such a student-learning conducive manner...it will become one of the classics. --John Stubbs, San Francisco State University In their earlier volumes, Singer & Berg have laid out the fundamentals of modern molecular biology. Here, with a group of the finest co-authors, they focus on the individual stories that make biology such a rich and varied science. The genes come alive as individual pieces of the biological tapestry. Viral genes, hemoglobin genes, genes for antibodies, genes of plants oncogenes and many more are probed along with the methodologies used to investigate them. A great volume from which to learn or teach about how actual life emerges from the four bases that make up DNA. --David Baltimore, President-Elect California Institute of Technology The textbook Exploring Genetic Mechanisms is an excellent account of the hallmarks of modern genetic analysis...[It] takes its readers through a detailed account of many fundamental principles of molecular genetics. It provides specific examples of well-characterized genetic mechanisms that operate within a gene family as well as examples of more complex genetic relations that operate within an entire organism. This book represents the next generation of modern genetics textbooks and will be invaluable for genetics researchers and students. --The New England Journal of Medicine


Author Information

Maxine Singer is the President of the Carnegie Institution of Washington and Scientist Emeritus at the NIH where she conducts research on transposable elements in the human genome. She is a member of the US National Academy of Sciences and its Institute of Medicine, and was awarded the National Medal of Science in 1992. Paul Berg is Willson Professor of Biochemistry and Director of the Beckman Center for Molecular and Genetic Medicine, Stanford University School of Medicine. He is a member of the US National Academy of Sciences and its Institute of Medicine. He was awarded the Nobel Prize in Chemistry in 1980, and received the National Medal of Science in 1983.

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