Overview

In this book, outstanding researchers from the US and Japan review recent progress in Epstein-Barr virus research. Most people carry EBV in memory B-cells in a latent stage. Many malignancies such as T/NK cell lymphoma, AIDS-associated B-cell lymphoma, gastric carcinoma and Hodgkin's disease have been causally linked to EBV. The development of molecular biology technique has allowed us to study the roles of individual EBV genes that act in the maintenance and disruption of EBV latency.

Full Product Details

Author:   K. Takada
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 2001
Volume:   258
Dimensions:   Width: 15.50cm , Height: 1.30cm , Length: 23.50cm
Weight:   0.391kg
ISBN:  

9783642625688

ISBN 10:   3642625681
Pages:   236
Publication Date:   05 November 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

List of Contents.- I Molecular Mechanisms of Maintenance and Disruption of Virus Latency.- EBV’s Plasmid Replicon: An Enigma in cis and trans.- Replication Licensing of the EBV oriP Minichromosome.- Epstein-Barr Virus Nuclear Protein 2-Induced Activation of the EBV-Replicative Cycle in Akata Cells: Analysis by Tetracycline-Regulated Expression.- Two Epstein-Barr Virus Glycoprotein Complexes.- EBV Replication Enzymes.- II EBV-Associated Malignancies.- Pathology and Molecular Pathology of Epstein-Barr Virus-Associated Gastric Carcinoma.- EBV and Malignant Lymphoma with Special Emphasis on Pyothorax-Associated Lymphoma.- AIDS Lymphoma: Its Virological Aspects.- III Molecular Mechanisms of Oncogenesis.- Role of Epstein-Barr Virus in Burkitt’s Lymphoma.- EBV Regulates c-MYC, Apoptosis, and Tumorigenicity in Burkitt’s Lymphoma.- Epstein-Barr Virus Infection of Human Epithelial Cells.- Characterization of EBV-Infected Epithelial Cell Lines from Gastric Cancer-Bearing Tissues.- IV Animal Model and New Therapeutic Approach to Malignancy.- A New Animal Model for Epstein-Barr Virus Pathogenesis.- Adoptive Immunotherapy of EBV-Associated Malignancies with EBV-Specific Cytotoxic T-Cell Lines.

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