Overview

Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.

Full Product Details

Author:   Zdenko Herceg ,  Toshikazu Ushijima ,  Theodore Friedman ,  Jay C. Dunlap
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Volume:   70
Dimensions:   Width: 15.20cm , Height: 2.90cm , Length: 22.90cm
Weight:   0.910kg
ISBN:  

9780123808660

ISBN 10:   0123808669
Pages:   394
Publication Date:   22 November 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Awaiting stock  

Table of Contents

Introduction, objectives of the book Zdenko Herceg and Toshikazu Ushijima Section I. Basic epigenetic mechanisms in the regulation of critical cellular processes DNA methylation and cancer Manel Esteller Histone modifications and cancer Zdenko Herceg Epigenetics and miRNAs in human cancer George A Calin Interplay between different epigenetic mechanisms Rabih Murr Section II. Epigenetic events underlying biological phenomena Genomic imprinting and cancer Eamonn Maher Epigenetic code and stem cells Yasuhiro Yamada Inheritance of epigenetic aberrations (constitutional epimutations) in cancer susceptibility Megan Hitchins Section III. Cancer epigenome Cancer epigenome Stephan Beck Identification of driver methylation by epigenomic analysis Gerd Pfeifer Epigenetic driver of genetic alterations Minoru Toyota Section VI. Epigenetic therapy and epigenetic drugs DNA demethylating agents and epigenetic therapy of cancer Mani Samson and Zdenko Herceg Histone modification therapy of cancer Severio Minucci

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