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OverviewEnzymes of Epigenetics, one of two new volumes in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods that are employed to study epigenetic regulation and includes structural, biochemical, molecular, biological, cellular, computational, and systems approaches. Topics include chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies and small molecule epigenetic regulators, and biological connections Full Product DetailsAuthor: Ronen Marmorstein (Perelman School of Medicine, University of Pennsylvania, USA)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Volume: 573 Dimensions: Width: 15.20cm , Height: 3.30cm , Length: 22.90cm Weight: 1.040kg ISBN: 9780128053652ISBN 10: 0128053658 Pages: 528 Publication Date: 14 July 2016 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsReviewsPraise for the Series: Should be on the shelves of all libraries in the world as a whole collection. - Chemistry in Industry The work most often consulted in the lab. - Enzymologia The Methods in Enzymology series represents the gold-standard. - Neuroscience Praise for the Series: Should be on the shelves of all libraries in the world as a whole collection. --Chemistry in Industry The work most often consulted in the lab. --Enzymologia The Methods in Enzymology series represents the gold-standard. --Neuroscience Praise for the Series: Should be on the shelves of all libraries in the world as a whole collection. - CHEMISTRY IN INDUSTRY The work most often consulted in the lab. - ENZYMOLOGIA The Methods in Enzymology series represents the gold-standard. - NEUROSCIENCE Author InformationDr. Marmorstein obtained his Ph.D. in Chemistry from the University of Chicago and, following a postdoctoral fellowship at Harvard University and a faculty appointment at The Wistar Institute, he joined the faculty at the Perelman School of Medicine at the University of Pennsylvania. Dr. Marmorstein is currently a Professor in the Department of Biochemistry and Biophysics and an Investigator in the Abramson Family Cancer Research Institute with adjunct appoints in the Department of Chemistry at the University of Pennsylvania and The Wistar Institute. The Marmorstein laboratory uses a broad range of molecular, biochemical and biophysical research tools centered on X-ray crystal structure determination to understand the chemical basis for the epigenetic regulation of gene expression. The laboratory is particularly interested in gene regulatory proteins and their upstream signaling kinases that are aberrantly regulated in cancer and other age-related disorders such as obesity and Alzheimer’s disease, and the use of high-throughput small molecule screening and structure-based design strategies towards the development of protein-specific small-molecule probes of protein function and for development into therapeutic agents. Tab Content 6Author Website:Countries AvailableAll regions |
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