Overview

This text presents a range of topics from the molecular events surrounding hormone actions to epidemiologic studies of the effects of environmental and occupational chemicals on reproductive organs. The endocrine systems covered include the adrenal cortex, thyroid and parathyroid, gonads, and the endocrine pancreas. Of particular importance are the chapters covering the general characteristics of the estrogen receptors and the androgen receptors. The book also describes some of the underlying toxic mechanisms involving pancreatic B cells and metal-induced changes in male sex accessory glands.

Full Product Details

Author:   John A. Thomas ,  Howard D. Colby
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Edition:   2nd edition
Dimensions:   Width: 15.60cm , Height: 2.50cm , Length: 23.40cm
Weight:   0.671kg
ISBN:  

9781560326137

ISBN 10:   1560326131
Pages:   339
Publication Date:   29 January 1997
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Preface Introduction 1. Chemically-Induced Injury of the Parathyroid Gland: Pathophysiology and Mechanistic Considerations 2. Physiology of the Thyroid Gland and Agents Affecting Its Secretion 3. Chemically-Induced Changes in the Thyroid 4. Toxicology of the Adrenal Cortex: Role o f Metabolic Activation 5. Chemically-Induced Lesions in the Adrenal Cortex 7. Xenoestrogens and Estrogen Receptor Action 8. Cellular and Molecular Effects of Androgenic-Anabolic Steroids 9. Role of Cadmium in the Etiology of Cancer of the Prostate10. Actions of Chemicals and Other Factors on Ley dig Cell Growth and Proliferation 11. Toxic Effects of Cyproheptadine and Its Analogs in Insulin-Producing Cells 12. Epidemiologic Evidence for Toxic Effects of Occupational and Environmental Chemicals on the Testes

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Author Information

John A. Thomas Vice President for Academic Services, Professor of Pharmacology, Department of Academic Service University of Texas Health Science Center, San Antonio, Texas. Howard D. Colby, Ph.D. Professor, Department of Pharmacology and Toxicology Philadelphia College of Pharmacy and Science, Philadelphia, Pennsylvania.

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