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OverviewLearn about the state of the art in building artificial membranes and synthetic biological devices, and in constructing mathematical models for their dynamics at multiple time and spatial scales with this comprehensive book. Drawing on recent advances in bioengineering and biochemistry, it describes how to engineer tethered bilayer lipid membranes, bioelectronic interfaces, high-resolution biosensors, and diagnostic devices for non-invasive cellular measurements and electroporation. Multi-physics models combining atomistic (molecular dynamics and coarse-grained molecular dynamics), mesoscopic (Poisson–Nernst–Planck), and macroscopic (reaction-rate theory) dynamics provide a complete structure-to-function description of these devices. Experiments and dynamic models explain how anti-microbial peptides penetrate membranes, how molecular machine biosensors built out of artificial membranes can detect femtomolar concentrations, and how electroporation can be controlled. Supported by atomistic simulation code online, this is essential reading for researchers, students and professionals in bioengineering, chemical engineering, biophysics, applied mathematics, and electrical engineering. Full Product DetailsAuthor: William Hoiles (University of British Columbia, Vancouver) , Vikram Krishnamurthy (Cornell University, New York) , Bruce Cornell (University of Technology Sydney)Publisher: Cambridge University Press Imprint: Cambridge University Press Dimensions: Width: 17.80cm , Height: 2.60cm , Length: 25.30cm Weight: 1.090kg ISBN: 9781108423502ISBN 10: 1108423507 Pages: 470 Publication Date: 03 May 2018 Audience: Professional and scholarly , College/higher education , Professional & Vocational , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationWilliam Hoiles is a Research Fellow in the Department of Electrical and Computer Engineering at the University of British Columbia, Vancouver. Vikram Krishnamurthy is a Professor in the School of Electrical and Computer Engineering and Cornell Tech at Cornell University, New York. He is a Fellow of the IEEE and the author of Partially Observed Markov Decision Processes (Cambridge, 2016). Bruce Cornell is an Adjunct Professor in the School of Life Sciences at the University of Technology Sydney, and at Western Sydney University. He is also the Principal Scientist at Surgical Diagnostics Pty Ltd and SDx Tethered Membranes Pty Ltd. Tab Content 6Author Website:Countries AvailableAll regions |
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