Overview

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor­ tunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung can­ cer, genitourinary cancer, and pediatric oncology; second, by asking emi­ nent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Full Product Details

Author:   Robert F. Ozols ,  Robert F Ozols
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 1989
Volume:   48
Dimensions:   Width: 15.50cm , Height: 1.20cm , Length: 23.50cm
Weight:   0.355kg
ISBN:  

9781461288862

ISBN 10:   146128886
Pages:   210
Publication Date:   27 September 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Drug resistance: The clinical problem.- 2. Mathematical models of drug resistance and chemotherapy effects.- 3. Multidrug resistance in human tumors.- 4. Structure and function of P—glycoprotein.- 5. Anthracycline resistance.- 6. Circumvention of drug resistance with calcium channel blockers and monoclonal antibodies.- 7. P—glycoprotein in breast cancer.- 8. Phosphoprotein, protein kinase C, and second-messenger system changes in human multidrug-resistant cancer cells.- 9. Alkylating agent resistance.- 10. Mechanisms of resistance to cisplatin and alkylating agents.- 11. Glutathione S—transferase and drug resistance.- 12. Tumor cell drug and radiation resistance: Does an interrelationship exist?.

Reviews

This book would be a helpful text for basic researchers, clinical investigators, and medical housestaff. It is well written and can be read in a relatively short period.' Breast Cancer Research and Treatment, 19, 1991 The book is an exciting survey of the potential application of laboratory data. It is a good example of interdisciplinary research collaboration. It is recommended reading for those engaged in the development of new treatment strategies.' Oncology, 48/1

`This book would be a helpful text for basic researchers, clinical investigators, and medical housestaff. It is well written and can be read in a relatively short period.' Breast Cancer Research and Treatment, 19, 1991 ` The book is an exciting survey of the potential application of laboratory data. It is a good example of interdisciplinary research collaboration. It is recommended reading for those engaged in the development of new treatment strategies.' Oncology, 48/1

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