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OverviewFull Product DetailsAuthor: Adeboye Adejare (Professor, Pharmaceutical Sciences, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Dimensions: Width: 19.10cm , Height: 1.90cm , Length: 23.50cm Weight: 0.750kg ISBN: 9780128028100ISBN 10: 0128028106 Pages: 316 Publication Date: 04 October 2016 Audience: Professional and scholarly , Professional & Vocational Replaced By: 9780443300080 Format: Hardback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of Contents1. General description of neurodegenerative disorders 2. Alzheimer’s disease diagnosis 3. National plan and resources to address Alzheimer’s disease 4. Current Medications for Treatment of Alzheimer's Disease: Acetylcholine esterase inhibitors and NMDA receptor antagonist 5. Physicochemical properties for potential AD drugs 6. Receptor approaches 7. Amyloid hypothesis 8. Tau proteins 9. Cholesterol and fat metabolism 10. Energy Metabolism 11. Simple in vivo models of Neurodegeneration (C. Elegans, fruitfly, and similar models) 12. Rodent Models 13. Clinical Trials 14. Non-pharmacologic Treatment ApproachesReviewsAuthor InformationAdeboye Adejare’s research group is interested in the areas of design and syntheses of small organic molecules to probe neurodegeneration, especially Alzheimer’s disease, and for treatment of cancer. They are also interested in in vitro models of drug absorption and ability to cross blood brain barrier; drug targeting; pharmaceutical profiling; and chemistry of fluoroaromatic compounds. The research is funded by the National Institutes of Health, the Office of Naval Research, and several pharmaceutical companies. These efforts have resulted in over 50 publications, 5 patents, and over 100 presentations at meetings, including invited presentations at national and international conferences. He also serves on several national panels, including those by NIH, NSF, and Alzheimer’s Association. Dr. Adejare is the editor of Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease which is also published by Elsevier. Tab Content 6Author Website:Countries AvailableAll regions |
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