Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers

Author:   Rajendra Awasthi (Professor, Department of Pharmaceutical Sciences, School of Health Sciences & Technology, University of Petroleum and Energy Studies, UPES, Dehradun, India) ,  Santosh Kumar Singh, PhD (Senior Scientist, Centre of Experimental Medicine and Surgery (CEMS), Faculty of Medicine, Institute of Medical Sciences, Banaras Hindu University, India) ,  Anurag Kumar Singh, PhD (Research Associate, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, India)
Publisher:   Elsevier - Health Sciences Division
ISBN:  

9780443248023


Pages:   600
Publication Date:   22 October 2025
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers


Overview

Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers delivers an up-to-date and complete overview of the range of biomedical applications for porous silicon nanomaterials, with a special emphasis on drug delivery. This book introduces the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, such as vaccine development, drug delivery, and tissue engineering. It also contains new insights on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, cancer immunotherapy, and more. Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers is of interest to researchers in the fields of materials science, nanotechnology, pharmaceutical science, biomedical engineering, and cancer research.

Full Product Details

Author:   Rajendra Awasthi (Professor, Department of Pharmaceutical Sciences, School of Health Sciences & Technology, University of Petroleum and Energy Studies, UPES, Dehradun, India) ,  Santosh Kumar Singh, PhD (Senior Scientist, Centre of Experimental Medicine and Surgery (CEMS), Faculty of Medicine, Institute of Medical Sciences, Banaras Hindu University, India) ,  Anurag Kumar Singh, PhD (Research Associate, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, India)
Publisher:   Elsevier - Health Sciences Division
Imprint:   Elsevier - Health Sciences Division
Weight:   0.450kg
ISBN:  

9780443248023


ISBN 10:   0443248028
Pages:   600
Publication Date:   22 October 2025
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Introduction to targeted, controlled, and responsive nanoscale drug delivery systems 2. Synthesis methods of porous silicon-based nanoparticles 3. Mesoporous silica nanoparticles for therapeutic uses 4. Mesoporous silicon-based nanocarriers for improvement of water-soluble drugs 5. Porous silicon-based nanocarriers for tumor targeting 6. Porous silicon and related composites for topical drug delivery 7. Porous silicon-based nanocarriers for neurodegenerative disorders 8. Functionalized silica-based nanocarriers for blood-brain barrier targeted delivery 9. Porous silicon-based materials in nano- and microneedles-based drug delivery systems 10. Porous silicon-based nanocarriers for cancer and immune therapy 11. Stimuli-responsive silica nanoparticles: Smart systems for controlled drug release 12. Mesoporous silica-based nanocarriers in pulmonary drug delivery 13. Porous silicon nanoparticles for improved cellular uptake and targeted drug delivery 14. Recent advances in porous silicon-based technology for biomedical applications 15. Immunotherapeutic applications of porous silicon 16. Modified porous silicon nanoparticles in drug delivery 17. Bioengineered porous silicon nanoparticles in vaccine development 18. Silica nanoparticles in clinical trials 19. Future perspectives of mesoporous silica-based nanocarriers

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Author Information

Rajendra Awasthi is Professor of Pharmaceutics at Department of Pharmaceutical Sciences, School of Health Sciences & Technology, University of Petroleum and Energy Studies, UPES, Dehradun, India. Santosh Kumar Singh is a Senior Scientist at the Centre of Experimental Medicine & Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. Dr. Anurag Kumar Singh is a Research Associate (ICMR-RA) in the Department of Pharmaceutical Engineering and Technology at IIT BHU, Varanasi. He earned his PhD from the Centre of Experimental Medicine and Surgery, IMS, BHU, and an M. Pharm from Central University of Rajasthan. With more than 3.5 years of postdoctoral experience, he has worked at Alabama State University (Cancer Biology Research and Training) and Bar-Ilan University (Institute of Nanotechnology & Advanced Materials, Israel). His research centers on nano-particulate systems for chronic pain, neurodegenerative disorders, and brain-targeted drug delivery, including dendrimers, nanoporous silica/silicon materials, and polymeric nanoparticles for controlled delivery. He aims to develop nanomedicines for biomedical applications and to bridge engineering, pharmaceutical, and medical research. He has published widely, including reviews/editorials, and authored/editor of four books and over ten book chapters.

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