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OverviewMany processes in the genetic life of the cell require a specific interaction between proteins and DNA. While DNA is normally thought of as a straight double helix, it can be distorted by bending and twisting, and these alterations are critical to a number of cellular processes. These include transcription (by which the genetic message is read), recombination (rearrangements by which new combinations of genes come about), and the repair of DNA damage. An interesting group of proteins have the important role of recognizing and manipulating DNA structure. This text explores the importance of DNA structure in the interactions between proteins and DNA in order to generate a new perspective on DNA-protein. Full Product DetailsAuthor: David M. J. Lilley (Director, CRC Nucleic Acid Structure Research Group)Publisher: Oxford University Press Imprint: Oxford University Press Volume: 7 Dimensions: Width: 19.00cm , Height: 1.30cm , Length: 24.60cm Weight: 0.498kg ISBN: 9780199634538ISBN 10: 019963453 Pages: 214 Publication Date: 13 July 1995 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Out of Print Availability: In Print  Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock. Table of Contents1: DNA-protein interaction at high resolution 2: DNA bending by sequence and proteins 3: Enzymes that supercoil DNA 4: Recognition of DNA damage and repair 5: Structure-recognition by DNA junction resolving enzymes 6: Site-specific recombinases and their interactions with DNA 7: The HMG-box domainReviews[T]he reader is left with a deep appreciation for the structural and mechanistic possibilities that have emerged from the long co-evolution of DNA and DNA-binding proteins. --Quarterly Review of Biology<br> Author InformationTab Content 6Author Website:Countries AvailableAll regions |
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