Overview

DNA in Health, Identity and Ancestry examines the human genome and advances in molecular techniques in relation to their value in health, genetic ancestry, and forensic DNA. This book systematically presents these three areas, providing new insights into recent developments in these fields, including gene editing, ancestral fraction determination, and DNA profiling. It covers the latest advances in molecular biology to understand the pertinent issues in these areas. DNA in Health, Identity and Ancestry provides an introduction to human genomes, and then delves into health, forensics and ancestry across 36 chapters. Each section is concluded with practical case studies to demonstrate the application of the principles discussed in each respective section. This book is a valuable resource for researchers, practitioners, and postgraduate students in biochemistry, molecular biology and genetics. It not only provides them with fundamental knowledge on genetics, diseases, population genetics and forensic DNA, but also presents advances, technical operational standards, analytical tools and recent developments in these respective areas.

Full Product Details

Author:   Hisham Atan Edinur, Ph.D. (Lecturer of Forensic Science Programme at Universiti Sains Malaysia, Malaysia) ,  Edward Kofi Abban, Ph.D. (Head of DNA Laboratory, Forensic Science Laboratory, Criminal Investigation Department, Ghana Police Service, Ghana) ,  Dibyajit Lahiri, B.Tech, M.Tech, PhD (Associate Professor, Department of Biotechnology, University of Engineering and Management, Kolkata, India)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.450kg
ISBN:  

9780443339479

ISBN 10:   0443339473
Pages:   522
Publication Date:   28 November 2025
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Forthcoming
Availability:   Not yet available  
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Table of Contents

1. Introduction to human genomes: nuclear and mitochondrial DNA 2. Genetic testing 3. Pharmacogenomics: current status and future prospects 4. Molecular diagnostics for infectious diseases 5. Donor and recipient matching for transfusion and transplantation surgery 6. Circulating DNA: origins, functions and profiling 7. Metagenomics of environmental samples 8. DNA extraction methods for pathogen analysis 9. DNA extraction methods for food analysis 10. Characterization and application of environmental DNA in multi-species biofilms 11. Y-chromosome: genetics, function and disease 12. X-chromosome: genetics, function and disease 13. Case study 14. STR (autosomal, Y and X chromosomes) and mtDNA profiling for casework and paternity cases 15. DNA databanking, hit matches and ethical issues 16. DNA profiling: technical and operating standards 17. Current progress in rapid DNA profiling and legal requirements 18. Forensic parameters inferred using autosomal STR data 20. Forensic parameters inferred using Y-STR population data 21. Forensic parameters inferred using X-STR data 22. Forensic parameters inferred using mtDNA data 23. Validation of newly developed STR typing kit 24. Developmental validation of extraction protocols for extracting DNA from crime scene samples 25. Novel markers for casework and paternity cases 26. Food forensics 27. Case study 28. Population genetics: markers and bioinformatics 29. Archaeogenetics of human history 30. Ancient DNA extraction and amplification techniques 31. Origins and migration patterns of indigenous people 32. Analysis of human leukocyte population data 33. Analysis of KIR population data 34. Analysis of genome wide SNP data 35. Genetic ancestry and health 36. Whole-genome sequence data and population structure 37. Admixture and selection in human evolution 38. Case study 39. Concluding remarks

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Author Information

Edinur H. Atan is a lecturer of Forensic Science Programme at Universiti Sains Malaysia, Malaysia and Research Fellow of Australian Research Centre for Human Evolution at Griffith University. He did his MSc in Forensic Science at Universiti Sains Malaysia and PhD in Cell and Molecular Biology at Victoria University of Wellington, New Zealand. In 2013, he settled into his current teaching and research role at Universiti Sains Malaysia. He has strong research skills in forensics, molecular biology, genetics and bio-medicine, an impressive list of articles and books published by reputable publishers (e.g. Springer, Lancet, Nature, MDPI, PLOS, Frontiers etc.) and contacts in US, UK, Australia, New Zealand plus Malaysia and elsewhere in Europe, Africa and Middle East. Dr Edward Kofi Abban started his forensic career in 2010 as the Head of the Police DNA laboratory in Ghana. He has over 13 years of experience as a DNA analyst with specialities spanning DNA profiling and DNA investigations form the crime scene to expert representations in courts, DNA-based Identification of missing persons and disaster victims. He is also lecturer in biology education at the at the University of Ghana. He earned his PhD in DNA profiling from the University Sains Malaysia and has contributed significantly to scholarship in areas such as forensic DNA database generation for relevant forensic markers and population genetics of Ghanaian and West African populations. His area of interest include population genetics, wildlife genetics and DNA profiling methodologies. Dibyajit Lahiri is Associate Professor in the Department of Biotechnology, University of Engineering & Management, Kolkata. His research interest is precisely on biofilm isolated from human prosthesis and its inhibition by various novel phyto and nano compounds. He is keen to explore the molecular mechanism behind the removal of biofilm by natural compounds. His research arena also encompasses computational drug development by using of bioinformatic. His work is regularly being presented and appreciated before a number of experts of National and International repute. He has more than 100 publications. Dr. Lahiri has edited 5 books. He is also in the role of associate editors of various journals of international reputes.

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