Overview

Addresses a number of basic principles underlying the vulnerability of the developing nervous system to environmental toxicant exposure. Evidence of functional alterations, induced at levels of chemical exposure that fail to produce structural teratological alterations, indicates that the evaluation of the functional capacity of exposed animals may indeed offer a sensitive evaluation of developmental toxicity. The contributing authors discuss the basic principles of development in structure and functional components and present information covering various methodological approaches, as well as evidence for the value of examining the developing nervous system for environmentally induced pertubations. The final chapter looks at how this data is used to evaluate human risk potential.

Full Product Details

Author:   G Jean Harry (National Inst. of Envir. Health, Res. Triangle Park, North Carolina)
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Dimensions:   Width: 15.60cm , Height: 1.80cm , Length: 23.50cm
Weight:   0.476kg
ISBN:  

9780849344275

ISBN 10:   0849344271
Pages:   192
Publication Date:   13 July 1994
Audience:   Professional and scholarly ,  Professional and scholarly ,  Professional & Vocational ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Introduction to Developmental Neurotoxicology (G.J. Harry). Neurotoxicants and Developing Brain (K. Suzuki and P.M. Martin). Experimental Models of Environmental Dysmyelination and Demyelination (R.C. Wiggins and G.W. Konat). Contribution of Recapitulation of Developmental Glial-Neuronal Interactions to the Neurodegeneration in Alzheimer's Disease: An Hypothesis (T.B. Shea). Second Messenger Systems in Developmental Neurotoxicity (L.G. Costa). Assessment of Motoric Effects (M.J. Kallman). Assessment of Learning and Memory in Developmental Neurotoxicology (M.E. Stanton). Developmental Neurotoxicology Risk Assessment (H.A. Tilson).

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions