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OverviewStudies in human patients and animal models of disease suggest a strong correlation between defects in dendrite development and common neurological disorders such as autism. Much of this book is thus dedicated toward highlighting recent advances in our understanding of the cellular and molecular mechanisms that regulate the development and maintenance of dendrites, a crucial component of neurons. The book begins by presenting the current state of knowledge on the building blocks or cell biology of dendrites. Mechanisms that sculpt the stereotypic architecture of dendritic arbors and shape their connectivity are also discussed, along with recent work describing how dendritic organization and connectivity are perturbed in disease. A unique aspect of the book is its exploration of diverse neuronal cell types across vertebrates and invertebrates, allowing a comparison of mechanisms across distinct circuits and species. The book comprises six parts, which cover the major advances in the field: Part 1, Introduction; Part 2, Basic Biology of Dendrites; Part 3, Patterning Dendritic Architecture of Neurons and Their Populations; Part 4, Cellular and Molecular Control of Dendrite Development and Maintenance; Part 5, Synapse Formation onto Dendrites; and Part 6, Dendrites in Disease. The book offers an excellent point of entry for students interested in neuroscience, as well as for clinicians. Full Product DetailsAuthor: Kazuo Emoto , Rachel Wong , Eric Huang , Casper HoogenraadPublisher: Springer Verlag, Japan Imprint: Springer Verlag, Japan Edition: Softcover reprint of the original 1st ed. 2016 ISBN: 9784431567646ISBN 10: 443156764 Pages: 608 Publication Date: 22 April 2018 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand We will order this item for you from a manufactured on demand supplier. Table of ContentsReviewsAuthor InformationKazuo Emoto: Professor, Department of Biological Sciences, The University of Tokyo, Japan Rachel Wong: Professor, Department of Structural Biology, University of Washington, USA Eric Huang: Professor, Department of Pathology, University of California San Francisco, USA Casper Hoogenraad: Professor, Department of Biology, Utrecht University, The Netherlands Tab Content 6Author Website:Countries AvailableAll regions |