Overview

Is the end of HIV upon us? Award-winning research scientist and HIV fellow at the Ragon Institute, Nathalia Holt, reveals the science behind the discovery of a functional cure and what it means for the millions affected by HIV and the history of the AIDS pandemic. Two men, known in medical journals as the Berlin Patients, revealed answers to a functional cure for HIV. Their cures came twelve years apart, the first in 1996 and the second in 2008. Each received his own very different treatment in Berlin, Germany, and each result spurred a new field of investigation, fueling innovative lines of research and sparking hope for the thirty-four million people currently infected with HIV. For the first time, Nathalia Holt, who has participated in some of the most fruitful research in the field, tells the story of how we came to arrive at this astounding and controversial turning point. Holt explores the two men's stories on a personal level, looking at how their experiences have influenced HIV researchers worldwide--including one very special young family doctor who took the time to look closely at his patients--and how they responded to their medications. Based on extensive interviews with the patients and their doctors as well as her own in-depth research, this book is an unprecedented look at how scientists pursue their inquiries, the human impact their research has, and what is and is not working in the relationship between Big Pharma and medical care.

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Reviews

"""A fascinating discourse on how medical science is zeroing in on an HIV vaccine after several anomalous triumphs...An astute AIDS retrospective blended with contemporary updates on aggressive medical strategies."" -- ""Kirkus Reviews"" ""In this accessible and fascinating account, Holt, a research scientist trained at MIT and Harvard...brings to light the remarkable early breakthroughs in treating a once fatal condition."" -- ""Publishers Weekly"""

Author Information

Nathalia Holt is a former fellow at the Ragon Institute of Massachusetts General Hospital, MIT, and Harvard University. Her writing has appeared in the Los Angeles Times, New York Times, TheAtlantic.com, Slate, Time.com, and Popular Science. Karen Saltus has narrated television and radio commercials, audiobooks, textbooks, and multimedia film and voice applications. She began her career thirty years ago at a radio station in Maine and in 1994 became a full-time freelance voice-over artist.

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