Overview

The Second Edinburgh International Workshop was held in September, 1984 and took as its topic the coordinated regulation of gene expression. The intention of this series of workshops is to promote exchange of ideas and data between scientists and clinicians whose interests span molecular and cell biology, development and differentiation, oncology, and genetic and developmental pathologies. It is hoped that such interdisciplinary discussions may give rise to fruitful insights. The meetings are structured to give ample time for discussion after each formal presentation and culminate in a session of general discussion which is reported at the end of the volume of proceedings. We are very grateful to the participants, all of whom participated in the discussion and whose contributions were essential to the success of the meeting. Novel ideas were often put forward and explored thoroughly from different angles. We normally expect to achieve quite rapid publication of the proceedings of the meeting and are grateful to authors who produced typescripts of their contributions expeditiously, but, as may sometimes be the case with multi-author works, some contributors had difficulty in meeting schedules for submitting manuscripts or corrections of the text of the discussion, and in one case we have been unable to publish any record of the contribution. Our committment to the publication of the discussion, allowing participants to make corrections to the transcript of the session, such as insertion of references and clarification of oral contributions, has also imposed some delay.

Full Product Details

Author:   R. Clayton
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 1986
Dimensions:   Width: 17.80cm , Height: 2.10cm , Length: 25.40cm
Weight:   0.765kg
ISBN:  

9781461293156

ISBN 10:   1461293154
Pages:   391
Publication Date:   27 September 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Transcriptional Controls.- Patterns of DNA Methylation and Expression of Genes.- Chromatin Structure and Protein-DNA Interactions in the 5?-Flanking Region of the Chicken Lysozyme Gene.- Nuclease Activation in Programmed Cell Death.- Regulation of Gene Expression.- Regulation of Alpha-Amylase Gene Expression.- Multiple Control Elements Associated with the Human ?-Globin Gene.- Coordinate Genotypic and Phenotypic Expression as Differentiation Markers in Human Lymphoid Malignancies.- Activation of RAS Oncogenes in Multistage Carcinogenesis of Mouse Skin.- The Interactions of Herpes Simplex Virus with Differentiated Cells.- Transformation of Human Cells by Viral and Cellular Oncogenes.- Tissue-Specific Expression of Cloned Chicken Crystallin Genes in Mammalian Cells.- The Expression of Genes Injected into Oocytes and Eggs of Xenopus Laevis.- Expression of Cloned Muscle-Specific Genes in Transfected Cells and Transgenic Mice.- Expression of the Exogenous Chicken ?-Crystallin Genes Incorporated in Mouse Teratocarcinoma Cells.- Developmental Events at the Cellular Level.- Extra-Lenticular Crystallins.- Glial Cell Lineages and Differentiation in the Rat Optic Nerve.- Regulation of Keratinization During the Development of the Avian Feather and Scutate Scale.- Communications Between Cells and the Construction of Tissues.- Responses of Metastatic Rhabdomyosarcoma Cells and Normal Myoblasts to Growth Factors Derived from Normal Tissues.- Comparison of the Effect of Fibroblast Growth Factor and Exogenous Extracellular Matrices on the Proliferation and Phenotypic Expression of Chondrocytes In Vitro.- Cells Into Organs.- Evolution of Gene Families and Control Mechanisms.- Crystallins: The Families of Eye Lens Proteins.- Immunological Analysis of ?-Crystallin Expressed in VariousTissues of the Chick In Vivo and In Vitro.- The Evolution of Control Mechanisms in Cellular Differentiation.- Final Discussion.- Coordinated Regulation of Gene Expression.- Demonstrations.- Quantitation and Localisation of Chick ?-Crystallin Gene Transcription in Developing Non-Lens Tissue.- Identification and Characterization of a Chick ?A2 Crystallin Genomic Clone and Preliminary Identification of a Chick ?-Cry stallin cDNA Clone.- Retinoic Acid is Lentoidogenic but Differentially Affects ?-Crystallin Expression by Chick Lens Cells In Vitro.- Contributors.

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