Overview

"Functional genomics has come of age. No longer is it an adventure for the avant garde scientist, but it has become an increasingly standardized mainstream tool accessible to any modern biological laboratory. Toxicogenomics studies are now generating an avalanche of data that, with the aid of established informatics methodology, is being translated into biologically meaningful information. This is enabling us to start harvesting the benefits from years of investment in terms of technology, time, and (of course) money. It is therefore timely to bring together leading toxicologists with a wide variety of scientific aims in this book to demonstrate how microarray technology can be successfully applied to different research areas. This book transects biology from bacteria to human, from ecologically relevant sentinel organisms to well-characterized model species, and represents the full toxicogenomics arena from exploratory ""blue sky"" science to the prospects for incorporation into regulatory frameworks."

Full Product Details

Author:   Christer Hogstrand (King's College London, UK) ,  Pete Kille (Cardiff University, UK)
Publisher:   Elsevier Science & Technology
Imprint:   Elsevier Science Ltd
Edition:   2nd edition
Volume:   v. 2
Dimensions:   Width: 15.20cm , Height: 2.00cm , Length: 22.90cm
Weight:   0.710kg
ISBN:  

9780444532749

ISBN 10:   0444532749
Pages:   352
Publication Date:   11 July 2008
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Daphnia Toxicogenomics Joseph R. Shaw, Dartmouth College Human Toxicogenomics Professor Joseph Lunec and Dr. Eugene Halligan, King's College London Metabolomics and Toxicogenomics Jake Bundy and Jeremy Nicholson, Imperial College Model Organisms of Environmental Toxicogenomics (Ecotoxicological model species - Daphnia, fathead minnow and zebrafish) Chris Vulpe, University of California, Berkely Non-model organism Toxicogenomics or Earthworm Toxicogenomics David Spurgeon, CEH Monks Wood Application of Toxicogenomics for study of endocrine disruption in fish Charles Tyler, Exeter Microbial Toxicogenomics Jason Snape, Astra-Zeneca Brixham Enviornmental Laboratories Comparative Toxicogenomics Jonathan Freedman, NIEHS

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