Overview

Dale's Principle postulated that a neuron functions as a metabolic unit, whereby a process occurring in the cell can influence all of the compartments of that given neuron. This was unfortunately transformed in the literature to a principle stating that “a single cell releases only one neurotransmitter”. Until recently, this has influenced many neuroscientists to consider with skepticism the idea that classical neurotransmitters could be co-released from neurons. It is now clear that the “one neuron, one neurotransmitter” postulate is the exception rather than the rule. The aim of this book is to gather the available evidence, provided by the authors that have discovered and studied the co-existence or co-release of several pairs of neurotransmitters, in several neural networks. It will provide a timely overview of a mechanism of neural communication that is likely to attract increasing attention of the neuroscientific community.

Full Product Details

Author:   Rafael Gutierrez
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of hardcover 1st ed. 2009
Dimensions:   Width: 15.50cm , Height: 1.60cm , Length: 23.50cm
Weight:   0.468kg
ISBN:  

9781441934987

ISBN 10:   1441934987
Pages:   236
Publication Date:   08 December 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Coexistence of Neuromessenger Molecules -- A Perspective.- : Out of One, Many.- Mechanisms of Synapse Formation: Activity-Dependent Selection of Neurotransmitters and Receptors.- Co-Release of Norepinephrine and Acetylcholine by Mammalian Sympathetic Neurons: Regulation by Target-Derived Signaling.- GABA, Glycine, and Glutamate Co-Release at Developing Inhibitory Synapses.- GABA is the Main Neurotransmitter Released from Mossy Fiber Terminals in the Developing Rat Hippocampus.- Postsynaptic Determinants of Inhibitory Transmission at Mixed GABAergic/Glycinergic Synapses.- Glutamate Co-Release by Monoamine Neurons.- Dopamine and Serotonin Crosstalk Within the Dopaminergic and Serotonergic Systems.- The Dual Glutamatergic/GABAergic Phenotype of Hippocampal Granule Cells.- Synaptic Co-Release of ATP and GABA.- The Co-Release of Glutamate and Acetylcholine in the Vertebrate Nervous System.- Colocalization and Cotransmission of Classical Neurotransmitters: An Invertebrate Perspective.- : Out of Many, One.

Reviews

Author Information

   

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions