Cloning Expression and Mutational Analysis of Human Interferon Alpha 2

Author:   Nasir Mahmood ,  M. Akhtar FRS ,  Naeem Rashid
Publisher:   VDM Verlag Dr. Muller Aktiengesellschaft & Co. KG
ISBN:  

9783639273526


Pages:   176
Publication Date:   03 April 2011
Format:   Paperback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Our Price $155.25 Quantity:  
Add to Cart

Share |

Cloning Expression and Mutational Analysis of Human Interferon Alpha 2


Add your own review!

Overview

The production of recombinant biopharmaceuticals with antiviral and antiproliferative properties is one of the major aims of advanced genetic engineering. Interferon alpha 2b belongs to the class of recombinant therapeutics which is equally effective against viral infections and carcinomas. Recombinant human IFN I 2b is widely used FDA approved protein drug with global sale level is expected to reach up to 5.8 billion US dollars by 2010 due to its increased demand as a result of high prevalence of hepatitis infections and carcinomas in developed as well as developing countries including Pakistan. In the current research a process was developed for the production of this recombinant interferon alpha 2b drug by adopting advanced molecular and biochemical strategies. Intragene modifications at specific amino acids were also made to produce antiviral gene sequences with improved antiviral properties. Human interferon alpha 2b gene analysis was also established in blood cancers (AML and ALL) in order to find out mutations of clinical significance in theses cancers.

Full Product Details

Author:   Nasir Mahmood ,  M. Akhtar FRS ,  Naeem Rashid
Publisher:   VDM Verlag Dr. Muller Aktiengesellschaft & Co. KG
Imprint:   VDM Verlag Dr. Muller Aktiengesellschaft & Co. KG
Dimensions:   Width: 22.90cm , Height: 1.00cm , Length: 15.20cm
Weight:   0.267kg
ISBN:  

9783639273526


ISBN 10:   3639273524
Pages:   176
Publication Date:   03 April 2011
Audience:   General/trade ,  General
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions
Latest Reading Guide

Aorrng

Shopping Cart
Your cart is empty
Shopping cart
Mailing List