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OverviewThe most feared attribute of the human pathogen Vibrio cholerae is its ability to cause outbreaks that spread like wildfire, completely overwhelming public health systems and causing widespread suffering and death. This volume starts with a description of the contrasting patterns of outbreaks caused by the classical and El Tor biotypes of V. cholerae. Subsequent chapters examine cholera outbreaks in detail, including possible sources of infection and molecular epidemiology on three different continents, the emergence of new clones through the bactericidal selection process of lytic cholera phages, the circulation and transmission of clones of the pathogen during outbreaks and novel approaches to modeling cholera outbreaks. A further contribution deals with the application of the genomic sciences to trace the spread of cholera epidemics and how this information can be used to control cholera outbreaks. The book closes with an analysis of the potential use of killed oralcholera vaccines to stop the spread of cholera outbreaks. Full Product DetailsAuthor: G. Balakrish Nair , Yoshifumi TakedaPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: Softcover reprint of the original 1st ed. 2014 Volume: 379 Dimensions: Width: 15.50cm , Height: 1.50cm , Length: 23.50cm Weight: 4.219kg ISBN: 9783662522714ISBN 10: 3662522713 Pages: 263 Publication Date: 23 August 2016 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand We will order this item for you from a manufactured on demand supplier. Table of Contents1 Cholera Outbreaks in the Classical Biotype Era – A.K. Siddique and Richard Cash 2. Cholera outbreaks in the El Tor Biotype Era and the Impact of the New El Tor Variants –Asish K. Mukhopadhyay, Yoshifumi Takeda and G. Balakrish Nair 3. Cholera Outbreaks in India – Thandavarayan Ramamurthy and Naresh C. Sharma 4. Cholera Outbreaks in South East Asia – Kaushik Bharati and S.K. Bhattacharya 5. Cholera Outbreaks in Africa – Martin Mengel, Isabelle Delrieu, Leonard Heyerdahl and Bradford D. Gessner 6. The Cholera Outbreak in Haiti: Where and How Did it Begin? – Daniele Lantagne, G. Balakrish Nair, Claudio F. Lanata and Alejandro Cravioto 7. Role of Phages in the Epidemiology of Cholera – Shah M. Faruque 8. Circulation and Transmission of Clones of Vibrio cholerae During Cholera Outbreaks – O. Colin Stine and J. Glenn Morris Jr. 9. Modelling Cholera Outbreaks – Dennis L. Chao, Ira M. Longini Jr. and J. Glenn Morris Jr. 10. Genomic science in Understanding Cholera Outbreaks and Evolution of Vibrio cholerae as a Human Pathogen. William P. Robins and John J. Mekalanos 11. When, How and Where Can Oral Cholera Vaccines be Used to Interrupt Cholera Outbreaks? – John Clemens and Jan Holmgren.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |