Cellular Osmolytes: From Chaperoning Protein Folding to Clinical Perspectives

Author:   Laishram Rajendrakumar Singh ,  Tanveer Ali Dar
Publisher:   Springer Verlag, Singapore
Edition:   Softcover Reprint of the Original 1st 2017 ed.
ISBN:  

9789811099472


Pages:   249
Publication Date:   09 May 2018
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Cellular Osmolytes: From Chaperoning Protein Folding to Clinical Perspectives


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Author:   Laishram Rajendrakumar Singh ,  Tanveer Ali Dar
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Verlag, Singapore
Edition:   Softcover Reprint of the Original 1st 2017 ed.
Dimensions:   Width: 15.50cm , Height: 1.70cm , Length: 23.50cm
Weight:   4.459kg
ISBN:  

9789811099472


ISBN 10:   9811099472
Pages:   249
Publication Date:   09 May 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

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Dr. Laishram R. Singh is an Assistant Professor at the University of Delhi. He obtained his Master’s degree from Jamia Millia Islamia, New Delhi. After receiving a doctoral degree in protein biophysics from Jamia Millia Islamia, Dr. Singh continued his postdoctoral research at Fox Chase Cancer Center, Philadelphia (FCCC). During his doctoral studies, he was engaged in investigating how small molecule compounds affect native protein structure, stability, and enzymatic catalysis. At the FCCC his main research interest was in understanding the proteostasis and modulators of mutant proteins including mutants of p53, cystathionine beta synthase, and methyl tetrahydrofolatereductase. Currently, Dr. Singh (at Delhi University) is investigating how dysregulated proteostasis, which is the common hallmark of many neurodegenerative and metabolic disorders, could be reversed. A prominent enzymologist and protein biochemist, Dr. Singh has authored more than 40 publications in many esteemed journals in the field of proteostatic regulation by small molecules and various heat shock proteins. He has also contributed chapters to several books published by Springer, InTech and Elsevier, etc., and is an active reviewer and Editorial Board member of several journals. Dr. Tanveer A. Dar is a senior Assistant Professor of Clinical Biochemistry at the University of Kashmir, India. He received his Master’s in biochemistry from Hamdard University, New Delhi, India, in 2003 and his PhD in biosciences from Jamia Millia Islamia, New Delhi in 2009. After completing his PhD, he engaged in a postdoctoral fellowship with Prof. Bruce E. Bowler at the University of Montana, USA. His main research area is protein structural biology and medicinal plant proteomics. He has published research papers in reputed international journals on protein folding and its stability in the presence of small molecule solutes. He is a recipient of Research Fellowships from the CSIR, NewDelhi, and the Indian National Science Academy. Dr. Dar is actively involved in various projects as principal investigator and co-investigator with funding from various reputed national funding agencies, e.g. the Department of Biotechnology and Department of Science and Technology, Govt. of India, New Delhi. His current research focuses on the modulation of protein fibrillation/aggregation by chemical chaperones and the characterization of therapeutically important proteins from medicinal plants.

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