Overview

This volume offers comprehensive reviews on the mechanism of cap-indepenent translation of viral and cellular mRNA molecules. The chapters include findings on cap-independent translation by internal ribosome binding of picornaviral, hepatitis C viral and certain cellular mRNAs and discuss the mechanisms underlying cap-independent translation of adenoviral and heat shock mRNAs. Using recent technologies in the field, features of the eukaryotic translational apparatus have been uncovered and their roles in translational initiation and its regulation are probed.

Full Product Details

Author:   Peter Sarnow
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Volume:   v.203
Weight:   0.430kg
ISBN:  

9783540591214

ISBN 10:   3540591214
Pages:   194
Publication Date:   16 August 1995
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Temporarily unavailable  
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Table of Contents

List of Contents.- Cap-Dependent and Cap-Independent Translation: Operational Distinctions and Mechanistic Interpretations.- Translation of Encephalomyocarditis Virus RNA by Internal Ribosomal Entry.- Anatomy of the Poliovirus Internal Ribosome Entry Site.- The Role of the La Autoantigen in Internal Initiation.- Structure and Function of the Hepatitis C Virus Internal Ribosome Entry Site.- Cap-Independent T ranslation in Adenovirus Infected Cells.- Cap-Independent Translation of Heat Shock Messenger RNAs.- Cap-Independent T ranslation and Internal Initiation of Translation in Eukaryotic Cellular mRNA Molecules.

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