Overview

This book presents an up-to-date and thorough overview of cancer of unknown primary, encompassing topics ranging from epidemiology, tumor biology, and prognostic factors through to the most recent diagnostic and therapeutic advances. All aspects of management are covered, including radiological, nuclear medicine, and pathological diagnosis, site-specific therapies, platinum-based combination chemotherapy, radiotherapy, and novel targeted treatments. Clear guidance is offered on diagnosis of the tissue of origin by means of gene expression and micro-RNA analyses and its therapeutic implications. Detailed directions are also provided on the identification of subsets of patients with a more favorable prognosis, in whom specific treatment offers the chance of long-term survival or even cure. Readers will find Cancer of Unknown Primary to be an ideal source of practically oriented information that will assist in delivery of the best possible care for patients with this challenging diagnosis.

Full Product Details

Author:   Alwin Krämer ,  Harald Löffler
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   1st ed. 2016
Dimensions:   Width: 15.50cm , Height: 1.70cm , Length: 23.50cm
Weight:   4.624kg
ISBN:  

9783319225807

ISBN 10:   3319225804
Pages:   194
Publication Date:   03 November 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Introduction.-  Epidemiology, risk factors and survival in CUP: pointers to disease mechanisms.- Biologic features of CUP.- Prognostic factors and their role in the management of CUP.- Diagnostic work-up of CUP – an approach to current recommendations and underlying evidence.- The radiologist’s approach to CUP.- Cancer of unknown primary: the pathologist’s approach.- Treatment of disseminated CUP.- Concepts of radiotherapy in cancer of unknown primary.- Favorable subsets of CUP.- Novel Diagnostic and Therapeutic Strategies in the Management of Patients with Cancers of Unknown Primary Site.- Future directions.

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