Overview

This book covers recent advances in all aspects of bone marrow-derived stem cells (BMSCs) for stroke treatment, while also providing comprehensive information on human clinical trials and animal models of stroke. In addition, it reviews the optimal conditions of transplantation for stroke therapy and potential mechanisms underlying transplanted cell-mediated functional recovery after stroke. As the first book to focus on BMSC therapy for stroke, it also discusses in depth the unique challenges of BMSCs-based therapy in this context.

Full Product Details

Author:   Kunlin Jin ,  Qichuan Zhuge ,  Xunming Ji
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Verlag, Singapore
Edition:   1st ed. 2017
Dimensions:   Width: 15.50cm , Height: 2.30cm , Length: 23.50cm
Weight:   7.077kg
ISBN:  

9789811029288

ISBN 10:   9811029288
Pages:   332
Publication Date:   23 December 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

The Preface.- Chapter 1 Ischemic stroke pathophysiology and cell therapy .- Chapter 2 Bone Marrow Stem Cells: Source, Characterization, Isolation, Culture and Identification .- Chapter 3 Mobilization and homing of bone marrow stem cells .- Chapter 4 Interaction of bone marrow stem cells with other cells .- Chapter 5 Mesenchymal stem cells for stroke therapy .- Chapter 6 Bone Marrow Hematopoietic Stem Cell Therapy in Stroke .- Chapter 7 Endothelial progenitor cells therapy in stroke .- Chapter 8 Co-transplantation strategies and combination therapies for stroke .- Chapter 9 Modification of bone marrow stem cells for homing and survival during cerebral ischemia .- Chapter 10 Clinical studies of bone marrow-derived stem cells therapy in stroke patients .- Chapter 11 Bone Marrow Stem Cell delivery methods, routes, time, efficacy and safety .- Chapter 12 Potential Mechanisms of Transplanted Cell-mediated Recovery After Stroke .- Chapter 13 Bone marrow stem cell stimulating factors and brain recovery after stroke .- Chapter 14 Imaging and tracking transplanted bone marrow stem cells after stroke.

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Author Information

Dr. Kunlin Jin is a tenured Professor at the University of North Texas Health Science Center, USA. His primary research interests are in aging and diseases. He has pursued research in several areas related to stroke and has made significant contributions concerning the treatment of brain diseases by cell replacement using stem cells. Dr. Jin has published over 200 research papers in prominent journals including JCI, PNAS, Nature, etc. and has a personal H-index of 56. Furthermore, he is Editor-in-Chief of the journal “Aging and Disease” and co-founder of the International Society on Aging and Disease.   Dr. Qichuan Zhuge is a Professor at the Department of Neurosurgery, Chairman of the Brain Center and Vice president at the first hospital of Wenzhou Medical University, China.   Dr. Xunming Ji is a Professor of Neurosurgery at Capital Medical University and Vice-President of Xuanwu Hospital, China. He was a principal investigator for National Science Fund for Distinguished Young Scholars of China (2013) and was a Cheung Kong Scholar of Ministry of Education of China (2014).

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