Bismuth-Ethanedithiol: A Potential Drug to Treat Biofilm Infections of Medical Devices Produced by Staphylococcus Epidermidis and Proteus Mirabilis

Author:   Jithendra Gunawardana
Publisher:   Dissertation.com
ISBN:  

9781599423043


Pages:   98
Publication Date:   26 August 2010
Format:   Paperback
Availability:   In Print   Availability explained
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Bismuth-Ethanedithiol: A Potential Drug to Treat Biofilm Infections of Medical Devices Produced by Staphylococcus Epidermidis and Proteus Mirabilis


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Overview

Staphylococcus epidermidis is the leading cause of hospital-acquired infections associated with implanted medical devices. Likewise, Proteus mirabilis is one of the leading causes of nosocomial Urinary Tract Infections (UTIs) and is associated with urinary catheter blockage. Both organisms produce biofilms, which make them less susceptible to antibiotics. Therefore, these infections are often notoriously difficult to treat and in many cases lead to complications. Preventing biofilm formation or killing a pre-existing biofilm would be useful solutions since biofilm formation is a phenomenon commonly observed in these organsims. This study investigated the in vitro efficacy of Bismuth-ethanedithiol (BisEDT) against biofilms produced by P. mirabilis and S. epidermidis. Anti-biofilm activity of BisEDT was evaluated in terms of inhibiting/preventing biofilm formation and eradicating/killing pre-formed biofilm produced by single species S. epidermidis and P. mirabilis.

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Author:   Jithendra Gunawardana
Publisher:   Dissertation.com
Imprint:   Dissertation.com
Dimensions:   Width: 18.90cm , Height: 0.50cm , Length: 24.60cm
Weight:   0.191kg
ISBN:  

9781599423043


ISBN 10:   1599423049
Pages:   98
Publication Date:   26 August 2010
Audience:   General/trade ,  General
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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