Biotechnology Engineering: A Practical Approach on Bioprocess Development from Lab to Industrial Scale

Author:   Vinayaka B. Shet (Assistant Professor, Department of Biotechnology Engineering, NMAMIT, Nitte, Karnataka, India) ,  Sandesh Kanthakere (Assistant Professor, Department of Biotechnology Engineering, NMAMIT, Nitte, Karnataka, India) ,  Nabisab Mujawar Mubarak (Associate Professor at the Faculty of Engineering, Univercity Technology Brunei, Brunei Darussalam) ,  Rama Rao Karri (Professor, Faculty of Engineering, University of Technology of Brunei, IUniversiti Teknologi Brunei, Brunei Darussalam)
Publisher:   Elsevier - Health Sciences Division
ISBN:  

9780443314766


Pages:   474
Publication Date:   29 August 2025
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Biotechnology Engineering: A Practical Approach on Bioprocess Development from Lab to Industrial Scale


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Author:   Vinayaka B. Shet (Assistant Professor, Department of Biotechnology Engineering, NMAMIT, Nitte, Karnataka, India) ,  Sandesh Kanthakere (Assistant Professor, Department of Biotechnology Engineering, NMAMIT, Nitte, Karnataka, India) ,  Nabisab Mujawar Mubarak (Associate Professor at the Faculty of Engineering, Univercity Technology Brunei, Brunei Darussalam) ,  Rama Rao Karri (Professor, Faculty of Engineering, University of Technology of Brunei, IUniversiti Teknologi Brunei, Brunei Darussalam)
Publisher:   Elsevier - Health Sciences Division
Imprint:   Elsevier - Health Sciences Division
Weight:   0.450kg
ISBN:  

9780443314766


ISBN 10:   0443314764
Pages:   474
Publication Date:   29 August 2025
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

PART A: Cell culture and Kinetic study 1. Culturing of microbial, animal and plant cells in lab scale 2. Microbial growth and cell kinetics 3. Design, optimization, and Inoculum development for culturing the cells 4. Lab scale studies on Submerged Liquid Fermentation (SLF) and Solid State Fermentation (SSF) PART B: Bioreactor handling and operation 5. Fundamental of Bioreactors and accessories 6. Design Aspects and Aseptic Maintenance of Bioreactors 7. Cleaning Techniques for Bioreactors and Regulatory Standards 8. Bioreactor sterilization techniques and equipment 9. Standard Operating Procedures and Auditing in Bioprocess Industries 10. Operation and control of Submerged Liquid Fermenters 11. Operation and control of submerged solid fermenters 12. Equipment for downstream Product Recovery and Purification 13. Modern Reactors and Software Tools in Bioprocess Development PART C: Bioreactor Scale up aspects and case studies 14. Scale-Up Rules and Reactor Accessories 15. Scale-Up Strategies for Submerged Liquid Fermentation 16. Scale-Up Strategies for Solid State Fermentation 17. Scale-Up Constraints from Lab Scale to Industrial Scale PART D: Bioproducts 18. Commercial Bioproducts from Bioreactors 19. Bioproducts from Fermentation and their Economic Impact 20. Manufacturing Techniques for Bioproducts

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Author Information

Dr. Vinayaka B Shet is an Associate Professor in the Department of Biotechnology Engineering, NMAMIT, off-campus centre, Nitte (Deemed to be university), Nitte, Karnataka, India. He holds a Ph.D. in Biotechnology from VTU Belgavi, an M.Tech. in Industrial Biotechnology from the National Institute of Technology Karnataka (NITK), and a B.E. in Biotechnology from P.A. College of Engineering, Mangaluru. He has over 18 years of experience in Academics, 10 years in Research, and 1 year in Industry. He received a young researcher award. He has published over 30 research articles and 10 book chapters and holds two Indian patents. He is a reviewer of various journals. He serves as Coordinator (Accreditation and Compliance) at Nitte (Deemed to be University), Mangaluru, India. Dr. Sandesh K is an Assistant Professor in the Department of Biotechnology Engineering, NMAMIT, off-campus centre, Nitte (Deemed to be university), Nitte, Karnataka, India. He holds a Ph.D. in Biotechnology from VTU Belgavi, and M.Tech. in Chemical Plant Design from the National Institute of Technology Karnataka (NITK), and B.E. in Chemical from B.M.S. College of Engineering, Bengaluru. He has over 14 years of experience in Academics and Research. He has many international and national publications in reputed journals and book chapters. He holds few Indian patents in his area of research. He is a reviewer of various journals. Dr Nabisab Mujawar Mubarak is an Associate Professor at the Faculty of Engineering, Universiti Teknologi Brunei, Brunei Darussalam. He is a scientific reviewer in numerous Chemical Engineering and Nano Technology journals. In research, Dr. Mubarak has published more than 400 journal papers and 40 conference proceedings, authored 80 book chapters, and has a 77 H-index. His areas of interest are carbon nanomaterial synthesis, magnetic biochar production using microwaves, and wastewater treatment using advanced materials. He receives the Curtin Malaysia Most Productive Research award, Outstanding Faculty of Chemical Engineering award, Best Scientific Research Award London, and Exceptional Scientist in publication and citation by i- Proclaim, Malaysia. Since 2020, he has also been listed in the top two percent of the world's most influential scientists in chemicals and energy. The List of the Top 2% of Scientists in the World compiled and published by Stanford University is based on their international scientific publications, the number of scientific citations for research, and participation in the review and editing of scientific research. Dr. Mubarak is a Fellow Member of the Institution of Engineers Australia, a Chartered Professional Engineer (CPEng) of The Institution of Engineers Australia, and a Chartered Chemical Engineer of the Institute of Chemical Engineering (IChemE), UK. He has published 11 books and is co-editor for ongoing Elsevier-edited books: 1) Nanomaterials for Carbon Capture and Conversion Technique, 2) Advanced Nanomaterials and nanocomposites for Bioelectrochemical Systems, 3) Water Treatment Using Engineered Carbon Nanotubes,4) Hybrid Nanomaterials for Sustainable Applications: Case Studies and Applications, 5), Sustainable Nanotechnology for Environmental Remediation, 6) Nanotechnology for Biomedical Applications,7) Nanotechnology for Electronic Applications, 8) Application of Bio-Additives for the Food Industry, 9) Contemporary Nanomaterials in Material Engineering Applications, 10)Fundamentals of Biomaterials: A Supplementary Textbook, 11) Emerging Water Pollutants: Concerns and Remediation Technologies. Dr. Rama Rao Karri is a Professor in the Faculty of Engineering at Universiti Teknologi Brunei. He holds a PhD from IIT Delhi and a Master’s from IIT Kanpur in Chemical Engineering. With over 20 years of experience in academia, industry, and research, he has experience working in multidisciplinary fields and has expertise in various evolutionary optimization techniques and process modelling. His expertise extends to process modeling and simulation, focusing on optimizing chemical and environmental processes to improve efficiency and sustainability. Dr. Karri serves on editorial boards of several international journals and acts as a peer reviewer for numerous reputed publications. He has held editorial roles including Editor-in-Chief and Associate Editor for journals such as Scientific Reports and the International Journal of Energy and Water Resources. He is also a guest editor for special issues on nanocomposites and environmental engineering topics. Additionally, Dr. Karri contributes to authoring and editing books on sustainable technologies, environmental remediation, and process monitoring with leading academic publishers. Prof. Dr. Mohammad Hadi Dehghani is a full professor at the Tehran University of Medical Sciences (TUMS), School of Public Health, Department of Environmental Health Engineering, Tehran, Islamic Republic of Iran. His scientific research interests include environmental science. He is the author of various research studies published in national and international journals and conference proceedings and head of several research projects at the TUMS. He has authored 20 books, 26 book chapters and more than 270 full papers published in peer-reviewed journals. He is an editorial board member, guest editor, and reviewer in many internal and international journals and a member of several international science committees worldwide. He also has the distinction of being listed in the top 2% of the world’s most influential scientists in the area of environmental sciences. He is a supervisor and advisor for many PhD and MSc theses at the TUMS. He is currently also a member of the Iranian Association of Environmental Health (IAEH) and member of the Institute for Environmental Research (IER) at the TUMS. He is an editor for 14 edited books (English): (1) Soft Computing Techniques in Solid Waste and Wastewater Management, (2) Environmental and Health Management of Novel Coronavirus Disease (COVID-19), (3) Green Technologies for the Defluoridation of Water, (4) Pesticide Remediation Technologies From Water and Wastewater, (5) COVID-19 and Sustainable Development Goals, (6) Industrial Wastewater Treatment: Emerging Technologies for Sustainability, (7) Sustainable Materials for Sensing and Remediation of Noxious Pollutants, (8) Wastewater-Based Epidemiology for the Assessment of Human Exposure to Environmental Pollutants, (9) Water Treatment Using Engineered Carbon Nanotubes, (10) Water, the Environment and the Sustainable Development Goals, (11) Sustainable Remediation Technologies for Emerging Pollutants in Aqueous Environment, (12) Health and Environmental Effects of Ambient Air Pollution, (13) Health Effects of Indoor Air Pollution, (14) Diseases Attributed to Air Pollution.

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