Overview

Bioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production.

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Dr. Surajbhan Sevda, completed Doctoral Degree in 2013 from Indian Institute of Technology Delhi, New Delhi, India. He is currently an Assistant Professor at the Department of Biotechnology, National Institute of Technology, Warangal, India. Prior to this, he was a technical officer (research scientist) at IIT Guwahati, India. He has published more than 28 articles in scientific journals and book chapters. He received his Bachelor of Engineering in Biotechnology and Master of Technology in fermentation technology from University of Rajasthan and Institute of Chemical Technology (formerly known as UDCT), University of Mumbai, India, in 2006 and 2008, respectively. He was a visiting scientist at University of Calgary, Canada in 2018. His research experience lies in the bioreactor design, modelling of microbial growth, biofuels, and bioenergy, life cycle analysis (LCA), metal recovery, biosensor development, green chemistry, microbial electrosynthesis, enzyme and antibiotic production. Dr. Sachin Kumar is currently working as Associate Professor at the Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, India. He obtained his Ph.D. in molecular virology from University of Maryland in 2010. His research area is viral Immunology, in broad sense, is the study of viral infections in context of immune responses to such infections which can cause deleterious effect on the functions of the cells. Viruses are highly adaptable and have developed ways to avoid detection by specific immune cells. Immune response to a virus follows a cascade of steps and different routes: via specific targeting cytotoxic immune cells, or chemicals such as interferon, or via antibody binding and subsequent complement system activation. Our current understanding of host immune responses to viruses has progressed in recent years, and 'Viral Immunology' as an area has established itself as a sub-discipline of 'Immunology' tackling the immunological context in viral infections.

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