Free Delivery Over $100
|
|
|||
|
||||
OverviewThis book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents structures of acridines with nucleic acids and proteins and compares them with the native structures. Furthermore, the book presents modern methods of acridine synthesis, comparing them with the most useful conventional methods. Acridines interact with both nucleic acids and proteins, and due to their direct interactions with various enzymes, they can be suitable for the treatment of neurodegenerative diseases, inflammation, immunological disorders, and protozoal diseases. The characteristic spectral properties of acridines can be employed in labeling proteins, nucleic acids, lipids, and even cells and their compartments. Moreover, they can be applied in photodynamic therapy. Full Product DetailsAuthor: Jan Ježek , Jan Hlaváček , Jaroslav ŠebestíkPublisher: Springer International Publishing AG Imprint: Springer International Publishing AG Edition: Softcover reprint of the original 1st ed. 2017 Volume: 72 Weight: 0.454kg ISBN: 9783319876801ISBN 10: 3319876805 Pages: 237 Publication Date: 11 August 2018 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsPreliminary ToC 1 Introduction.- 2 Nomenclature.- 3. Syntheses.- 4. Interactions of acridines with nucleic acids.- 5. Intercations with proteins.- 6. Applications for treament of neurodegenerative diseases.- 7. Some applications of selective toxicities of acridines.- 8. Acridine on dendrimeric carriers.- 9 Acridines used for staining.- 10 Miscellaneous.- 11 Conclusions and outlook.ReviewsAuthor Information
Tab Content 6Author Website:Countries AvailableAll regions |
||||
