Overview

The survival of the human species has improved significantly in modern times. During the last century, the mean survival of human populations in developed countries has increased more than during the preceding 5000 years. This improvement in survival was accompanied by an increase in the number of active years. In other words, the increase in mean life span was accompanied by an increase in health span. This is now accentuated by progress in medicine reducing the impact of physiologic events such as menopause and of patho­ logical processes such as atherosclerosis. Up to now,research on aging, whether theoretical or experimental, has not contributed to improvement in human survival. Actually, there is a striking contrast between these significant modifications in survival and the present knowledge of the mechanisms of human aging. Revealed by this state of affairs are the profound disagreements between gerontologists in regard to the way oflooking at the aging process. The definition of aging itself is difficult to begin with because of the variability of how it occurs in different organisms.

Full Product Details

Author:   Alvaro Macieira-Coelho
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 2003
Volume:   30
Dimensions:   Width: 15.50cm , Height: 1.00cm , Length: 23.50cm
Weight:   0.320kg
ISBN:  

9783642623981

ISBN 10:   3642623980
Pages:   192
Publication Date:   30 September 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Historical and Current Concepts of the Mechanisms of Aging.- 1.1 Rate of Living.- 1.2 Endocrine Theory.- 1.3 Weismann’s Theory.- 1.4 The Immune Theory.- 1.5 Cross-Linking.- 1.6 Free Radicals.- 1.7 Aging and Evolution.- Basic Determinants of Longevity.- 2.1 Energy Intake and Expenditure.- 2.2 The Storage and Flow of Information.- 2.3 Redundancy.- 2.4 Genetics of Aging.- Aging of the Mammalian Organism.- 3.1 Cellular Aging.- 3.2 Connective Tissue.- 3.3 The Structural Reorganization of the Mammalian Organism.- Neoplastic Growth Through the Human Life Span.- 4.1 The Clinical Age — Incidence of Neoplastic Disease.- 4.2 The Heterogeneity of Neoplastic Growth.- 4.3 Initiation of Neoplastic Growth at the Cellular Level.- 4.4 Progression of Neoplastic Disease.- 4.5 Age-Dependent Sensitivity to Carcinogens.- 4.6 Deviations from Normal Development and Neoplastic Growth.- The Centenarians.- References.

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions