Biological Responses to Nanoscale Particles: Molecular and Cellular Aspects and Methodological Approaches

Author:   Peter Gehr ,  Reinhard Zellner
Publisher:   Springer Nature Switzerland AG
Edition:   1st ed. 2019
ISBN:  

9783030124632


Pages:   344
Publication Date:   29 October 2020
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Our Price $206.97 Quantity:  
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Biological Responses to Nanoscale Particles: Molecular and Cellular Aspects and Methodological Approaches


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Overview

In this book the recent progress accumulated in studies of the interaction of engineered nanoparticles with cells and cellular constituents is presented. The focus is on manufacturing and characterization of nanosized materials, their interactions with biological molecules such as proteins, the mechanisms of transport across biological membranes as well as their effects on biological functions. Fundamental molecular and cellular aspects are in the foreground of the book. A further particularity is the interdisciplinary approach, including fields such as preparatory and analytical chemistry, biophysics and the physics of colloids, advanced microscopy and spectroscopy for in-situ detection of nanoparticles, cellular toxicology and nanomedicine. Nanoscale particles are known to exhibit novel and unprecedented properties that make them different from their corresponding bulk materials. As our ability to control these properties is further advanced, a huge potential to create materials with novel properties and applications emerges. Although the technological and economic benefits of nanomaterials are indisputable, concerns have also been raised that nanoscale structuring of materials might also induce negative health effects. Unfortunately, such negative health effects cannot be deduced from the known toxicity of the corresponding macroscopic material. As a result, there is a major gap in the knowledge necessary for assessing their risk to human health.

Full Product Details

Author:   Peter Gehr ,  Reinhard Zellner
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   1st ed. 2019
Weight:   0.557kg
ISBN:  

9783030124632


ISBN 10:   3030124630
Pages:   344
Publication Date:   29 October 2020
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Introduction.- Manufacturing methods and characterization (with respect to size, shape, surface properties, coatings, charge etc.)- Interactions of nanoparticles with proteins.- Membrane transfer mechanisms.-Cellular uptake and intracellular trafficking of nanoparticles.- Cellular responses and health effects.

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