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Author:   Jonathan Pevsner (The Johns Hopkins School of Medicine, Baltimore, MD, USA)
Publisher:   John Wiley and Sons Ltd
Imprint:   Wiley-Blackwell
Edition:   3rd edition
Dimensions:   Width: 21.80cm , Height: 4.80cm , Length: 27.90cm
Weight:   2.495kg
ISBN:  

9781118581780

ISBN 10:   1118581784
Pages:   1168
Publication Date:   23 October 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In stock  
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Table of Contents

Part I Analyzing DNA, RNA, and Protein Sequences 1 Introduction 3 2 Access to Sequence Data and Related Information 19 3 Pairwise Sequence Alignment 69 4 Basic Local Alignment Search Tool (BLAST) 121 5 Advanced Database Searching 167 6 Multiple Sequence Alignment 205 7 Molecular Phylogeny and Evolution 245 Part II Genomewide Analysis of DNA, RNA, and Protein 8 DNA: The Eukaryotic Chromosome 307 9 Analysis of Next-Generation Sequence Data 377 10 Bioinformatic Approaches to Ribonucleic Acid (RNA) 433 11 Gene Expression: Microarray and RNA-seq Data Analysis 479 12 Protein Analysis and Proteomics 539 13 Protein Structure 589 14 Functional Genomics 635 Part III Genome Analysis 15 Genomes Across the Tree of Life 699 16 Completed Genomes: Viruses 755 17 Completed Genomes: Bacteria and Archaea 797 18 Eukaryotic Genomes: Fungi 847 19 Eukaryotic Genomes: From Parasites to Primates 887 20 Human Genome 957 21 Human Disease 1011 Glossary 1075 Self-Test Quiz: Solutions 1103 Author Index 1105 Subject Index 1109

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Author Information

Jonathan Pevsner, PhD, is a Professor in the Department of Neurology at Kennedy Krieger Institute, an internationally recognized institution dedicated to improving the lives of children with neurodevelopmental disorders. He holds a primary faculty appointment as Professor in the Department of Psychiatry and Behavioral Sciences (Johns Hopkins University School of Medicine). He holds joint or secondary appointments in the Department of Neuroscience, the Institute of Genetic Medicine, and the Division of Health Sciences Informatics (Johns Hopkins School of Medicine), and the Department of Molecular Microbiology and Immunology (Johns Hopkins Bloomberg School of Public Health). He has taught bioinformatics courses since 2000 at the Johns Hopkins School of Medicine, and was awarded Teacher of the Year honors by the Graduate Student Association in both 2001 and 2006, the Professors' Award for Excellence in Teaching awarded by the medical faculty (2003), Teacher of the Year (Advanced Academic Programs, 2009), and Teaching Excellence Award in the Johns Hopkins Bloomberg School of Public Health (2011). In 2013 his lab used whole genome sequencing and reported a mutation that causes a rare disease, Sturge-Weber syndrome, as well as a commonly occurring port-wine stain birthmark.

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