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OverviewThe text reviews current data on all the different biochemical steps that comprise base excision repair (BER), the primary pathway for removal of alkylation, hydrolytic and oxidative damage to DNA. It covers various aspects from excision of damaged or mismatched bases and repair of baseless sites, through a discussion of the DNA polymerases needed for BER, and eventually to the enzymes that complete the BER process. Where appropriate, the cytotoxic and mutagenic consequences of a failure to complete any particular step in the process are outlined. Full Product DetailsAuthor: I.D. Hickson (University of Oxford)Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Weight: 0.493kg ISBN: 9783540629825ISBN 10: 3540629823 Pages: 192 Publication Date: 01 August 1997 Audience: College/higher education , Professional and scholarly , Postgraduate, Research & Scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In stock We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |