Overview

"Bacterial plasmids originating in a wide range of genera are being studied from a variety of perspectives in hundreds of laboratories around the globe. These elements are well known for carrying ""special"" genes that confer important survival properties, frequently neces­ sary under atypical conditions. Classic examples of plasmid-borne genes are those provid­ ing bacterial resistance to toxic substances such as antibiotics, metal ions, and bacte­ riophage. Often included are those determining bacteriocins, which may give the bacterium an advantage in a highly competitive environment. Genes offering metabolic alternatives to the cell under nutritionally stressed conditions are also commonly found on plasmids, as are determinants important to colonization and pathogenesis. It is likely that in many, if not most, cases plasmids and their passenger determinants represent DNA acquired recently by their bacterial hosts, and it is the characteristic mobility of these elements that enables their efficient establishment in new bacterial cells by the process known as conjugation. Whereas many plasmids are fully capable of promoting their own conjugal transfer, others move only with help from coresident elements. The ability of a plasmid to establish itself in a variety of different species is com­ mon, and recent studies have shown that transfer can in some cases occur from bacterial cells to eukaryotes such as yeast."

Full Product Details

Author:   D.B. Clewell
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   Softcover reprint of the original 1st ed. 1993
Dimensions:   Width: 17.80cm , Height: 2.50cm , Length: 25.40cm
Weight:   1.650kg
ISBN:  

9780306443763

ISBN 10:   0306443767
Pages:   413
Publication Date:   31 May 1993
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Genetic Organization of TransferRelated Determinants on the Sex Factor F and Related Plamids (K. IppenIhler, R.A. Skurray). Key Regulatory Aspects of Transfer of FRelated Plasmids (W.B. Dempsey). Broad HostRange Conjugative and Mobilizable Plasmids in GramNegative Bacteria (D.G. Guiney). DNA Processing and Replication During Plasmid Transfer Between GramNegative Bacteria (B. Wilkins, E. Lanka). Mobilization of Chromosomes and Nonconjugative Plasmids by Cointegrative Mechanisms (C. Reimmann, D. Haas). Conjugative Pili and PilusSpecific Phages (L. Frost). Plasmid Incompatibility and Replication Control (B.L. Kittell, D.R. Helsinki). Conjugal Transfer in Anaerobic Bacteria (F.L. Macrina). Sex Pheromones and the PlasmidEncoded Mating Response in Enterococcus faecalis (D.B. Clewell). The Conjugative Transposons of GramPositive Bacteria (D.B. Clewell, S.E. Flannagan). 6 additional articles. Index.

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