Overview

Since the subject of arenaviruses was visited by Current Topics in Microbiology and Immunology 14 years ago, enormous advances have been made in this area. The receptor for several arenaviruses, alpha-dystroglycan, was identified, the replication strategy of these viruses was decoded, and application of a reverse genetics system for studying viral gene function and viral biology is well underway. In addition to reviewing these advances, Volume I includes discussion of arenaviral molecular phylogeny, reservoirs in rodents and clinical diseases caused by both new world and old world arenaviruses.

Full Product Details

Author:   Michael B. A. Oldstone
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   illustrated edition
Volume:   Vol 262
Weight:   0.434kg
ISBN:  

9783540422440

ISBN 10:   3540422447
Pages:   217
Publication Date:   26 February 2002
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Temporarily unavailable  
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Table of Contents

List of Contents.- Molecular Phylogeny of the Arenaviruses.- Mammalian Reservoirs of Arenaviruses.- Human Infection with Arenaviruses in the Americas.- Lassa Fever.- Receptor Structure, Binding, and Cell Entry of Arenaviruses.- Arenaviruses: Genomic RNAs, Transcription, and Replication.- Arenaviruses: Protein Structure and Function.- Reverse Genetics of Arenaviruses.

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