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OverviewThis book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community. This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology. Full Product DetailsAuthor: Katharina Urmann , Johanna-Gabriela WalterPublisher: Springer Nature Switzerland AG Imprint: Springer Nature Switzerland AG Edition: 1st ed. 2020 Volume: 174 Weight: 0.506kg ISBN: 9783030540609ISBN 10: 303054060 Pages: 215 Publication Date: 01 August 2020 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand We will order this item for you from a manufactured on demand supplier. Table of ContentsBiophysical Characterization of Aptamer-Target Interactions.- Impedimetric Aptamer-based Biosensors: Principles and Techniques.- Impedimetric Aptamer-based Biosensors: Applications.- Aptamer-based affinity chromatography for protein extraction and purification.- Aptamers in diagnostic and molecular imaging applications.- Aptamer-modified nanoparticles in medical applications.- Defining Target Product Profiles (TPPs) for Aptamer based diagnostics.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |