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OverviewRecent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a critical requirement. There is an unprecedented urgency for aspiring and practicing clinicians to become trained on how to interpret data from pharmacogenomic testing in preparation for the future of healthcare—i.e., personalized medicine. Applying Pharmacogenomics in Therapeutics provides timely coverage of the principles, practice, and potential of pharmacogenomics and personalized medicine. Comprised of chapters contributed by well-established pharmacologists and scientists from US and Chinese academia and industry, this authoritative text: Demonstrates how to apply the principles of pharmacogenomics and its biotechnologies in patient care Depicts the use of genetic biomarkers in drug discovery and development, laboratory medicine, and clinical services Describes the practice of pharmacogenomics in the treatment of cancers, cardiovascular diseases, neurologic and psychiatric disorders, and pulmonary diseases Discusses the merging of pharmacogenomics and alternative medicine, as well as the integration of pharmacogenomics into pharmacoeconomics Each chapter begins with the key concepts, followed by in-depth explorations of case reports or critical evaluations of genetic variants/biomarkers, and concludes with questions for self-examination. Full Product DetailsAuthor: Xiaodong Feng , Hong-Guang XiePublisher: Taylor & Francis Inc Imprint: CRC Press Inc Dimensions: Width: 15.60cm , Height: 2.30cm , Length: 23.40cm Weight: 0.566kg ISBN: 9781466582675ISBN 10: 1466582677 Pages: 312 Publication Date: 27 January 2016 Audience: Professional and scholarly , Professional and scholarly , Professional & Vocational , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsConcepts in Pharmacogenomics and Personalized Medicine. Principles of Pharmacogenetic Biotechnology and Testing in Clinical Practice. Essential Pharmacogenomic Biomarkers in Clinical Practice. Applying Pharmacogenomics in Drug Discovery and Development. Pharmacogenomics and Laboratory Medicine. Clinical Applications of Pharmacogenomics in Cancer Therapy. Clinical Applications of Pharmacogenomics in Drug Therapy of Cardiovascular Diseases. Clinical Applications of Pharmacogenomics in Drug Therapy of Neurologic and Psychiatric Disorders. Applying Pharmacogenomics in the Therapeutics of Pulmonary Diseases. Pharmacogenomics and Alternative Medicine: Merge of Future and Tradition. Pharmacoeconogenomics: A Good Marriage of Pharmacoeconomics and Pharmacogenomics.ReviewsThe book exemplifies clinical cases of genetic variants in several diseases, defining genetic determinants for drug response and thoroughly describes the applications and therapy in clinical practice. Finally, the authors connect pharmacogenomics with the generation of cost-effectiveness treatments. Applying Pharmacogenomics in Therapeutics is intended for graduate, medical school courses. or healthcare professionals with a deep focus on genomics, pharmacy, pharmacology, and clinical care practice. Healthcare providers and research scientists would benefit from this text as a reference tool of the recent advances in this field. This text is well written and provides useful examples, tables and clinical cases to better understand and practice the concepts being described. Each chapter begins with a short list of key concepts, an introduction to the topic of the chapter, and concludes with a summary and study questions to practice. The book facilitates an extensive number of references per chapter to educate in depth and to provide tools to increase research and knowledge to the readers. Overall, this text is a comprehensive presentation of the recent approaches in personalized therapy based on genome sequencing and pharmacology combination. - Judit Jimenez-Sainz, The Yale Journal of Biology and Medicine, vol. 90, March 2017 Author InformationXiaodong Feng, PhD, PharmD, began his biomedical research career 19 years ago in the Wound Healing Center, Stony Brook School of Medicine, Stony Brook, New York, USA. He then served for four years as assistant professor in the Department of Dermatology at the State University of New York at Stony Brook, USA. Currently, Dr. Feng is professor of Pharmacology and Oncology, and Associate Dean at California Northstate University College of Medicine, Elk Grove, USA; clinical pharmacist at Sutter Davis Hospital, California, USA; and oncology pharmacy specialist at Dignity Health Medical Foundation, Rancho Cordova, California, USA. Hong-Guang Xie, MD, PhD, earned his degrees from Central South University Xiangya School of Medicine, Changsha, China, was promoted to lecturer, and then to associate professor of pharmacology. Subsequently, he served as co-founder and associate director of the Pharmacogenetics Research Institute, Changsha, China; postdoctoral research fellow and faculty research instructor at Vanderbilt University, Nashville, Tennessee, USA; staff research fellow at the University of California Washington Center, DC, USA; and Oak Ridge Institute for Science and Education (ORISE) fellow for the United States Food and Drug Administration (US FDA). Dr. Xie is currently full professor of pharmacology and chief of the General Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, China. Tab Content 6Author Website:Countries AvailableAll regions |
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