Overview

This significantly revised fourth edition provides a practically orientated guide to interactions associated with antiseizure medications. It describes pharmacokinetic and pharmacodynamic antiseizure medication (ASM) interactions, including details of the magnitude and mechanism of interactions, and also of drug combinations that are not associated with interactions and therefore can be co-prescribed without undue concern.  Presented in alphabetical order and by drug class, drug interactions that occur between ASMs and also between ASMs and non- ASMs are described in three sections: Drug interactions between ASMs; Drug interactions between ASMs and non- ASM Drugs: Interactions affecting ASMs; Drug interactions between ASMs and non ASM Drugs: Interactions affected by ASMs. The latest data on all drug interactions is presented. New agents discussed include cannabidiol, cenobamate, everolimus and fenfluramine,. Antiseizure Medication Interactions: A Clinical Guide, 4th Edition concisely presents the most recent developments and data available on the topic. Therefore, enabling physicians and allied health professionals to make more rational choices when ASM polytherapy regimens are required. It will be of interest to medical professionals in disciplines including neurology, psychiatry and pediatrics. 

Full Product Details

Author:   Philip N. Patsalos
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   4th ed. 2022
Weight:   0.575kg
ISBN:  

9783030827892

ISBN 10:   3030827895
Pages:   357
Publication Date:   02 January 2022
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.
Language:   English

Table of Contents

Section 1 – Introduction.- Section 2 – Drug Interactions Between AEDs.- Acetazolamide.- Cannabidiol.-  Carbamazepine.- Clobazam.- Clonazepam.- Ethosuximide.- Eslicarbazepine acetate.- Felbamate.- Fenfluramine.- Gabapentin.- Lacosamide.- Lamotrigine.- Levetiraceta.- Methsuximide.- Oxcarbazepine.- Perampanel.- Phenobarbital.- Phenytoin.- Piracetam.- Pregabalin.- Primidone.- Rufinamide.- Stiripentol.- Tiagabine.- Topiramate.- Valproic Acid.- Vigabatrin.- Zonisamide.- Section 3 – Drug Interactions between AEDs and non-AED drugs: Interactions Affecting AEDs.- Acetazolamide.- Cannabidiol.- Carbamazepine.- Clobazam.- Clonazepam.- Ethosuximide.- Eslicarbazepine acetate.- Felbamate.- Fenfluramine.- Gabapentin.- Lacosamide.- Lamotrigine.- Levetiracetam.- Methsuximide.- Oxcarbazepine.- Perampanel.- Phenobarbital.- Phenytoin.- Piracetam.- Pregabalin.- Primidone.- Rufinamide.- Stiripentol.- Tiagabine.- Topiramate.- Valproic Acid.- Vigabatrin.- Zonisamide.- Section 4– Drug Interactions between AEDs and non-AED drugs: Interactions Affected by AEDS.- Analgesics.- Antimicrobials.- Antineoplastic agents.- Antiulcer drugs.- Cardiovascular drugs.- Immunosuppressants.- Neuromuscular Blocking Agents.- Psychotropic Drugs.- Steroids.- Miscellanea. 

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Author Information

Philip Patsalos is an Emeritus Professor of Clinical Pharmacology at University College London's Queen Square Institute of Neurology, Department of Clinical and Experimental Epilepsy, London UK. His clinical and research interests relate to the therapeutics of epilepsy and include: new drug treatments and strategies, new drug development (Phase II and III trials) and formulations, pharmacokinetic profiling and drug interactions. He has in excess of 230 publications (books, book chapters and peer reviewed papers) and has served on various International League Against Epilepsy (ILAE) committees (including the Commission on Therapeutic Strategies, the Commission on Generics, the Sub-Commission on Polytherapy and Drug Interaction and the Sub-Commission on Therapeutic Drug Monitoring) and International Association of Therapeutic Drug Monitoring and Clinical Toxicology committees (including the Clinical Pharmacokinetics Committee and the Impact of Therapeutic Drug Monitoring on Pharmacoeconomics Committee). He was recently awarded the 2016 Excellence in Epilepsy Lifetime Achievement Award by the British Branch ILAE for his contribution to epilepsy care and research.  

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