Overview

This work is focused on a specific family of calcium and membrane-binding proteins, annexins, ubiquitously spread within living organisms, including animals, plants and fungi. It covers important areas of annexinology. The characterization of structural-functional relationship within the annexin family of proteins, together with emerging transgenic animal models, provides an up-to-date overview of potential physiological roles of annexins. Growing evidence of participation of annexins in human diseases, called annexinopathies, related to disturbances in signal transduction, vesicular traffic, ion homeostasis and energy metabolism within the cell.

Full Product Details

Author:   Joanna Bandorowicz-Pikula
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   2003 ed.
Dimensions:   Width: 15.50cm , Height: 2.40cm , Length: 23.50cm
Weight:   0.659kg
ISBN:  

9780306478345

ISBN 10:   030647834
Pages:   273
Publication Date:   31 July 2003
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Preface; J. Bandorowicz-Pikula. Structure, function and evolution of the annexin gene superfamily; M.P. Fernandez, R.O. Morgan. Structural conservation and functional versatility: allostery as a common annexin feature; A. Hofmann, R. Huber. Self-assembly of Annexin A5 on lipid membranes; N. Govorukhina, W. Bergsma-Schutter, C. Mazères-Dubut, S. Mazères, E. Drakopoulou, L. Bystrykh, F. Oling, A. Mukhopadhyay, I. Reviakine, J. Lai Kee Him, A. Brisson. Annexin gene knock-out models; A. Tomas, M.J. Hayes, D. Roy, B. Young, S.E. Moss. Annexin V: stimulation-dependent association with membrane protein; E. Tzima, J.H. Walker. Annexin 1 crystal structure interaction of annexins with membranes; A. Rosengarth, H. Luecke. Annexin II heterotetramer analysis of a pleiotropic protein; N.R. Filipenko, D.M. Waisman. Role of annexin VI in receptor-mediated endocytosis, membrane trafficking and signal transduction; T. Grewal, C. Enrich, S. Jackle. Annexins and tissue mineralization matrix vesicles, ion channel activity of annexins and annexin V/collagen interactions; T. Kirsch. Acidic pH-induced ion channels formed by annexin VI transformation from soluble to membrane integral protein; S. Pikula. Annexinopathy in the antiphospholipid syndrome; J.H. Rand, Xiao-Xuan Wu. Annexins and phospholipases; A.G. Buckland, D.C. Wilton. Role of annexin II tetramer in the regulation of plasmin activity; Kyu-Sil Choi, D.K. Fogg, S. Fitzpatrick, D.M. Waisman. The nucleotide face of annexins; J. Bandorowicz-Pikula. Involvement of human annexins in viral entry; E. Depla.

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