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Author:   Christoph Fahlke
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   1st ed. 2024
Volume:   283
Weight:   0.790kg
ISBN:  

9783031513459

ISBN 10:   3031513452
Pages:   362
Publication Date:   05 January 2024
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

​Preface.- Muscle chloride channels.- Adrenal anion channels - new roles in zona glomerulosa physiology and in the pathophysiology of primary aldosteronism.- ClC-K Kidney Chloride Channels : from structure to pathology.- Biophysical and pharmacological insights to CLC chloride channels and Transporters.- Function and regulation of the calcium-activated chloride channel anoctamin 1.- Structure and function of calcium-activated chloride channels and scramblases in TMEM16 family.- Structural basis for anion-selective Cys-loop receptor signal transduction and modulation.- Physiological functions of the volume regulated anion channel VRAC/LRRC8 and the proton-activated chloride channel PAC/TMEM206.- CFTR modulators: from mechanism to targeted therapeutics.- Structure, physiology, and pharmacology of chloride-dependent cation cotransporters.- SLC26 Anion Transporters.- Pharmacology of Na-dependent transporters of inorganic phosphate.- Simulation of fluoride anions in CLC proteins: from potent inhibition to selective transport.

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